CHRONIC PERIODONTITIS AND ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH ARTHERIAL HYPERTENSION

The work offers a view at the data obtained through an examination of 120 patients with chronic generalized periodontitis (CP) and arterial hypertension (AH). The check-up included clinical examination, immunohistochemical, morphometric studies, as well as evaluation of the endothelium vasodilating function. CP in patients with hypertension features more significant changes in the quantitative density of gum cells positive to ET-1, endothelial NO-synthase, if compared to the CP values in patients with no background somatic pathology. Changes affecting vasoactive mediators in the gum are associated with a systemic inflammatory response and a violation of the endothelium vasodilating function. Periodontitis remission can be achieved with the therapy of the neurotransmitter imbalance.