The possible involvement of microRNAs in preeclampsia and gestational diabetes mellitus

被引：40
|
作者：
Pillar, Nir [1 ]
Yoffe, Liron [1 ]
Hod, Moshe [1 ,2 ]
Shomron, Noam [1 ]
机构：
[1] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel
[2] Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
来源：
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY | 2015年 / 29卷 / 02期
关键词：
preeclampsia; gestational diabetes mellitus; biomarker; early detection; microRNA; RECOMMENDATIONS; PREDICTION; MECHANISMS; EXPRESSION; ECLAMPSIA; IMPACT; TYPE-2; CELL;
D O I：
10.1016/j.bpobgyn.2014.04.021
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Great obstetrical syndromes is a collective name for several complications of pregnancy that affect >15% of pregnancies. They may confer adverse pregnancy outcomes and maternal and fetal morbidity, and require close medical monitoring and treatment. The etiology, pathogenesis, and outcome of these syndromes are obscure in the majority of cases. All appear during mid-to-late pregnancy with no reliable biomarkers for early detection and possibly prevention at present. This article focuses on the quest for early reliable markers for preeclampsia and gestational diabetes mellitus (GDM) development, mainly on the involvement of microRNA in the pathogenesis and its possible role as an early biomarker for disease development. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：176 / 182
页数：7
相关论文
共 50 条
  • [1] MicroRNAs and Exosomal microRNAs May Be Possible Targets to Investigate in Gestational Diabetes Mellitus
    Yang, Xiyao
    Wu, Na
    DIABETES METABOLIC SYNDROME AND OBESITY, 2022, 15 : 321 - 330
  • [2] The possible involvement of circRNA DMNT1/p53/JAK/STAT in gestational diabetes mellitus and preeclampsia
    Bao, Dongqin
    Zhuang, Chaohui
    Jiao, Yan
    Yang, Li
    CELL DEATH DISCOVERY, 2022, 8 (01)
  • [3] Insulin resistance and preeclampsia in gestational diabetes mellitus
    Montoro, MN
    Kjos, SL
    Chandler, M
    Peters, RK
    Xiang, AH
    Buchanan, TA
    DIABETES CARE, 2005, 28 (08) : 1995 - 2000
  • [4] A Big Role for microRNAs in Gestational Diabetes Mellitus
    Masete, Matladi
    Dias, Stephanie
    Malaza, Nompumelelo
    Adam, Sumaiya
    Pheiffer, Carmen
    FRONTIERS IN ENDOCRINOLOGY, 2022, 13
  • [5] Differential expression of candidate circulating microRNAs in maternal blood leukocytes of the patients with preeclampsia and gestational diabetes mellitus
    Hocaoglu, Meryem
    Demirer, Selin
    Senturk, Hilal
    Turgut, Abdulkadir
    Komurcu-Bayrak, Evrim
    PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH, 2019, 17 : 5 - 11
  • [6] Gestational Diabetes Mellitus and Preeclampsia: Correlation and Influencing Factors
    Yang, Ying
    Wu, Na
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, 9
  • [7] Progress in Research on Biomarkers of Gestational Diabetes Mellitus and Preeclampsia
    Liu, Yang
    Li, Dan Yang
    Bolatai, Alayi
    Wu, Na
    DIABETES METABOLIC SYNDROME AND OBESITY, 2023, 16 : 3807 - 3815
  • [8] The Impact of Coexisting Gestational Diabetes Mellitus on the Course of Preeclampsia
    Pankiewicz, Katarzyna
    Szczerba, Ewa
    Fijalkowska, Anna
    Sierdzinski, Janusz
    Issat, Tadeusz
    Maciejewski, Tomasz Mikolaj
    JOURNAL OF CLINICAL MEDICINE, 2022, 11 (21)
  • [9] Risk assessment for preeclampsia in women with gestational diabetes mellitus
    Phaloprakarn, Chadakarn
    Tangjitgamol, Siriwan
    JOURNAL OF PERINATAL MEDICINE, 2009, 37 (06) : 617 - 621
  • [10] Circulating MicroRNAs for Early Diagnosis of Gestational Diabetes Mellitus
    Moon, Hanna
    Moon, Jooyoung
    METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 116 : 46 - 46
12345