Diastereoselective addition of organotitanium reagents to chiral γ-hydroxybutenolides

被引:0
|
作者
Miles, William H. [1 ]
Duca, Daniela G. [1 ]
Freedman, Jaryd T. [1 ]
Goodzeit, Elliot O. [1 ]
Hamman, Kristin B. [1 ]
De Sousa, Chiquita A. Palha [1 ]
Selfridge, Brandon R. [1 ]
机构
[1] Lafayette Coll, Dept Chem, Easton, PA 18042 USA
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D O I
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The addition of (i-PrO)(3)TiCH3 to gamma-hydroxybutenolides having a chiral center with an alkoxy group adjacent to the ketone functionality (of the open chain form) gave gamma-lactones in good yields and high diastereoselectivity.
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页码:195 / 198
页数:4
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