Immediate reaction to roxithromycin and prick test cross-sensitization to erythromycin and clarithromycin

被引:24
|
作者
Kruppa, A [1 ]
Scharffetter-Kochanek, K [1 ]
Krieg, T [1 ]
Hunzelmann, N [1 ]
机构
[1] Univ Cologne, Dept Dermatol, D-50924 Cologne, Germany
关键词
antibiotic; side effect; allergy; acute urticaria;
D O I
10.1159/000017907
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Allergic reactions to macrolides appear to be very rare. Only a few cases of fixed drug eruption or urticaria due to the administration of erythromycin have been reported. Cross-reactions between the different macrolides have not yet been published. We report a case of a 31-year-old female patient who developed generalized urticaria and tachycardia shortly after administration of roxithromycin (Rulid(R)). Immediate-type hypersensitivity was confirmed by positive prick test reactions to roxithromycin and the chemically closely related macrolides erythromycin and clarithromycin.
引用
收藏
页码:335 / 336
页数:2
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