Chemoradiotherapy for fistula-related perianal squamous cell carcinoma with Crohn's disease

被引:2
|
作者
Sakanaka, Katsuyuki [1 ]
Fujii, Kota [1 ]
Hirashima, Hideaki [1 ]
Mukumoto, Nobutaka [1 ]
Inoo, Hiroyuki [1 ]
Narukami, Ryo [1 ]
Sakai, Yoshiharu [2 ]
Mizowaki, Takashi [1 ]
机构
[1] Kyoto Univ, Grad Sch Med, Dept Radiat Oncol & Image Appl Therapy, Sakyo Ku, 54 Shogoin Kawahara Cho, Kyoto 6068507, Japan
[2] Kyoto Univ, Grad Sch Med, Dept Surg, Sakyo Ku, 54 Shogoin Kawahara Cho, Kyoto 6068507, Japan
关键词
Crohn's disease; Fistula-unrelated perianal squamous cell carcinoma; Chemoradiotherapy; RADIATION-THERAPY; MITOMYCIN;
D O I
10.1007/s13691-021-00497-9
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The reports of chemoradiotherapy for anal squamous cell carcinoma with Crohn's disease are few. Severe toxicity related to radiotherapy is concerned in patients with inflammatory bowel disease. We report a case of chemoradiotherapy for locally advanced fistula-related perianal squamous cell carcinoma in a patient with long-standing Crohn's disease which was controlled by a maintenance therapy. The patient completed standard chemoradiotherapy using intensity-modulated radiotherapy without severe toxicity, and achieved complete remission. Standard chemoradiotherapy using intensity-modulated radiotherapy may be feasible and effective treatment for this population when Crohn's disease is controlled.
引用
收藏
页码:305 / 311
页数:7
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