Semi-automated mitral valve morphometry and computational stress analysis using 3D ultrasound

被引：34

作者：

Pouch, Alison M. ^{[2
]}

Xu, Chun ^{[1
]}

Yushkevich, Paul A. ^{[3
]}

Jassar, Arminder S. ^{[1
]}

Vergnat, Mathieu ^{[1
]}

Gorman, Joseph H., III ^{[1
]}

Gorman, Robert C. ^{[1
]}

Sehgal, Chandra M. ^{[3
]}

Jackson, Benjamin M. ^{[1
]}

机构：

[1] Univ Penn, Dept Surg, Philadelphia, PA 19104 USA

[2] Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA

[3] Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA

来源：

JOURNAL OF BIOMECHANICS | 2012年 / 45卷 / 05期

关键词：

Mitral valve; Image processing; 3D echocardiography; Finite element analysis; 3-DIMENSIONAL ECHOCARDIOGRAPHY; REGURGITATION; OPTIMIZATION; REGISTRATION; DISEASE; REPAIR; ROBUST; SHAPE;

D O I：

10.1016/j.jbiomech.2011.11.033

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

In vivo human mitral valves (MV) were imaged using real-time 3D transesophageal echocardiography (rt-3DTEE), and volumetric images of the MV at mid-systole were analyzed by user-initialized segmentation and 3D deformable modeling with continuous medial representation, a compact representation of shape. The resulting MV models were loaded with physiologic pressures using finite element analysis (FEA). We present the regional leaflet stress distributions predicted in normal and diseased (regurgitant) MVs. Rt-3DTEE, semi-automated leaflet segmentation, 3D deformable modeling. and FEA modeling of the in vivo human MV is tenable and useful for evaluation of MV pathology. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：903 / 907

页数：5

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