β(1-3)Glucanosyltransferase Gel4p Is Essential for Aspergillus fumigatus

被引:83
|
作者
Gastebois, Amandine [1 ]
Fontaine, Thierry [1 ]
Latge, Jean-Paul [1 ]
Mouyna, Isabelle [1 ]
机构
[1] Inst Pasteur, Unite Aspergillus, F-75724 Paris 15, France
关键词
CELL-WALL; FUNGAL CELL; FAMILY; MORPHOGENESIS; VIABILITY; SYNTHASE; PROTEIN;
D O I
10.1128/EC.00107-10
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The beta(1-3) glucanosyltransferase GEL family of Aspergillus fumigatus contains 7 genes, among which only 3 are expressed during mycelial growth. The role of the GEL4 gene was investigated in this study. Like the other Gelps, it encodes a glycosylphosphatidylinositol (GPI)-anchored protein. In contrast to the other beta(1-3)glucanosyltransferases analyzed to date, it is essential for this fungal species.
引用
收藏
页码:1294 / 1298
页数:5
相关论文
共 50 条
  • [1] Deletion of GEL2 encoding for a β(1-3)glucanosyltransferase affects morphogenesis and virulence in Aspergillus fumigatus
    Mouyna, I
    Morelle, W
    Vai, M
    Monod, M
    Léchenne, B
    Fontaine, T
    Beauvais, A
    Sarfati, J
    Prévost, MC
    Henry, C
    Latgé, JP
    MOLECULAR MICROBIOLOGY, 2005, 56 (06) : 1675 - 1688
  • [2] A novel beta-(1-3)-glucanosyltransferase from the cell wall of Aspergillus fumigatus
    Hartland, RP
    Fontaine, T
    Debeaupuis, JP
    Simenel, C
    Delepierre, M
    Latge, JP
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (43) : 26843 - 26849
  • [3] Characterization of a New β(1-3)-Glucan Branching Activity of Aspergillus fumigatus
    Gastebois, Amandine
    Mouyna, Isabelle
    Simenel, Catherine
    Clavaud, Cecile
    Coddeville, Bernadette
    Delepierre, Muriel
    Latge, Jean-Paul
    Fontaine, Thierry
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (04) : 2386 - 2396
  • [4] Two α(1-3) glucan synthases with different functions in Aspergillus fumigatus
    Beauvais, A
    Maubon, D
    Park, S
    Morelle, W
    Tanguy, A
    Huerre, M
    Perlin, DS
    Latgé, JP
    APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2005, 71 (03) : 1531 - 1538
  • [5] Aspergillus fumigatus exoβ(1-3)glucanases family GH55 are essential for conidial cell wall morphogenesis
    Millet, Nicolas
    Moya-Nilges, Maryse
    Sachse, Martin
    Locker, Jacomina Krijnse
    Latge, Jean-Paul
    Mouyna, Isabelle
    CELLULAR MICROBIOLOGY, 2019, 21 (12)
  • [6] Aspergillus fumigatus β(1-3) Glucanases involved in conidial Cell Wall morphogenesis
    Millet, N.
    MEDICAL MYCOLOGY, 2018, 56 : S126 - S126
  • [7] A 1,3-β-glucanosyltransferase isolated from the cell wall of Aspergillus fumigatus is a homologue of the yeast Bgl2p
    Mouyna, I
    Hartland, RP
    Fontaine, T
    Diaquin, M
    Simenel, C
    Delepierre, M
    Henrissat, B
    Latgé, JP
    MICROBIOLOGY-SGM, 1998, 144 : 3171 - 3180
  • [8] Molecular characterization of a cell wall-associated β(1-3)endoglucanase of Aspergillus fumigatus
    Mouyna, I
    Sarfati, J
    Recco, P
    Fontaine, T
    Henrissat, B
    Latge, JP
    MEDICAL MYCOLOGY, 2002, 40 (05) : 455 - 464
  • [9] The Aspergillus fumigatus β-1,3-glucanosyltransferase Gel7 plays a compensatory role in maintaining cell wall integrity under stress conditions
    Zhao, Wan
    Li, Chunli
    Liang, Jingnan
    Sun, Shufeng
    GLYCOBIOLOGY, 2014, 24 (05) : 418 - 427
  • [10] Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus
    Andrea Doni
    Raffaella Parente
    Ilaria Laface
    Elena Magrini
    Cristina Cunha
    Federico Simone Colombo
    João F. Lacerda
    António Campos
    Sarah N. Mapelli
    Francesca Petroni
    Rémi Porte
    Tilo Schorn
    Antonio Inforzato
    Toine Mercier
    Katrien Lagrou
    Johan Maertens
    John D. Lambris
    Barbara Bottazzi
    Cecilia Garlanda
    Marina Botto
    Agostinho Carvalho
    Alberto Mantovani
    Nature Communications, 12