Selective Photodepletion of Recipient-Alloreactive T-Cells Enables Safe and Efficacious Haploidentical HSCT: Initial Results from a Phase 2 Trial in Patients with AML, ALL, and MDS

被引：7

作者：

Roy, Denis-Claude ^{[1
]}

Maertens, Johan ^{[2
]}

Walker, Irwin ^{[3
]}

Lachance, Silvy ^{[1
]}

Roy, Jean ^{[1
]}

Foley, Stephen Ronan ^{[3
]}

Lewalle, Philippe ^{[4
]}

Selleslag, Dominik L. D. ^{[5
]}

De Jong, Liesbeth ^{[6
]}

Velthuis, Jurjen H. L. ^{[6
]}

Gerez, Lisya ^{[6
]}

Reitsma, Karen ^{[6
]}

Wagena, Edwin ^{[6
]}

Mielke, Stephan ^{[7
]}

机构：

[1] Univ Montreal, Hop Maisonneuve Rosemont, Montreal, PQ, Canada

[2] Univ Hosp Gasthuisberg Leuven, Leuven, Belgium

[3] Juravinski Hosp & Canc Ctr, Hamilton, ON, Canada

[4] ULB, Inst Jules Bordet, Brussels, Belgium

[5] Acad Hosp St Jan, Brugge, Belgium

[6] Kiadis Pharma, Amsterdam, Netherlands

[7] Univ Klinikum Wurzburg, Wurzburg, Germany

来源：

BLOOD | 2014年 / 124卷 / 21期

关键词：

D O I：

10.1182/blood.V124.21.38.38

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：4

共 8 条

[1] SELECTIVE PHOTODEPLETION OF RECIPIENT-ALLOREACTIVE T-CELLS ENABLES SAFE AND EFFICACIOUS HAPLOIDENTICAL HSCT: INTERIM RESULTS FROM A PHASE II TRIAL IN PATIENTS WITH AML, ALL, AND MDS
Roy, D. -C.
Maertens, J.
Walker, I.
Foley, R.
Lewalle, P.
Selleslag, D.
Velthuis, J.
Gerez, L.
Reitsma, K.
Wagena, E.
Roy, J.
Lachance, S.
Mielke, S.
BONE MARROW TRANSPLANTATION, 2014, 49 : S221 - S221
[2] SELECTIVE DEPLETION OF RECIPIENT-ALLOREACTIVE T-CELLS WHILE RETAINING VIRAL-SPECIFIC AND MEMORY T-CELLS ENABLES SAFE AND EFFICACIOUS HAPLO-IDENTICAL HSCT
Velthuis, J.
De Jong, L.
Boumedine, R. S.
Giard, M.
Roy, D.
Ruediger, M.
CYTOTHERAPY, 2014, 16 (04) : S19 - S19
[3] Selective Depletion of Recipient-Alloreactive T-Cells While Retaining Viral-Specific and Memory T-Cells Enables Safe and Efficacious Haplo-Identical HSCT
Velthuis, Jurjen H. L.
De Jong, Liesbeth
Boumedine, Radia Sidi
Giard, Marie-Pier
Roy, Denis-Claude
Ruediger, Manfred
BLOOD, 2014, 124 (21)
[4] SELECTIVE DEPLETION OF RECIPIENT-ALLOREACTIVE T-CELLS WHILE RETAINING VIRAL-SPECIFIC AND MEMORY T-CELLS ENABLES SAFE AND EFFICACIOUS HAPLO-IDENTICAL HSCT
Velthuis, J.
De Jong, L.
Boumedine, R. Sidi
Giard, M. -P.
Roy, D. -C.
Ruediger, M.
BONE MARROW TRANSPLANTATION, 2014, 49 : S127 - S128
[5] Donor lymphocytes depleted of alloreactive T-cells (ATIR101) improve overall survival and reduce transplant related mortality in a T-cell depleted haploidentical HSCT: Results from a Phase 2 trial in patients with AML and ALL
Roy, D. -C.
Lachance, S.
Roy, J.
Walker, I.
Maertens, J.
Cohen, S.
Foley, S. R.
Lewalle, P.
Olavarria, E.
Selleslag, D.
Ruediger, M.
Velthuis, J.
Reitsma, K.
Gerez, L.
Rovers, J.
Boenig, H.
Mielke, S.
BONE MARROW TRANSPLANTATION, 2016, 51 : S27 - S28
[6] Donor Lymphocytes Depleted of Alloreactive T-Cells (ATIR101) Improve Event-Free Survival (GRFS) and Overall Survival in a T-Cell Depleted Haploidentical HSCT: Phase 2 Trial in Patients with AML and ALL
Roy, Denis-Claude
Lachance, Silvy
Roy, Jean
Walker, Irwin
Maertens, Johan
Delisle, Jean-Sebastien
Foley, Stephen Ronan
Lewalle, Philippe
Olavarria, Eduardo
Selleslag, Dominik
Ruediger, Manfred
Velthuis, Jurjen
Gerez, Lisya
Rovers, Jeroen
Bonig, Halvard
Mielke, Stephan
BLOOD, 2016, 128 (22)
[7] IMMUNOTHERAPY WITH DONOR LYMPHOCYTES DEPLETED OF ANTI-HOST REACTIVE CELLS RESULTS IN SAFE AND EFFICACIOUS HAPLOIDENTICAL HSCT: INTERIM RESULTS FROM A PHASE II TRIAL IN PATIENTS WITH HEMATOLOGIC MALIGNANCIES
Roy, D.
Maertens, J.
Walker, I.
Foley, R.
Lewalle, P.
Selleslag, D.
Velthuis, J.
Gerez, L.
Reitsma, K.
Wagena, E.
Roy, J.
Lachance, S.
Mielke, S.
CYTOTHERAPY, 2014, 16 (04) : S27 - S27
[8] Donor Lymphocytes Depleted of Alloreactive T-Cells (ATIR101) Reduce Transplant Related Mortality and Improve Overall Survival in Haploidentical HSCT for Patients with AML and ALL, Using an Immunosuppressant-Free Transplant Regimen
Roy, Denis-Claude
Lachance, Silvy
Roy, Jean
Walker, Irwin
Maertens, Johan
Cohen, Sandra
Foley, Stephen Ronan
Lewalle, Philippe
Olavarria, Eduardo
Selleslag, Dominik
Rudiger, Manfred
Velthuis, Jurjen
Reitsma, Karen
Gerez, Lisya
Rovers, Jeroen
Bonig, Halvard
Mielke, Stephan
BLOOD, 2015, 126 (23)

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