Treatment strategies for myeloproliferative neoplasms

被引:0
|
作者
Heidel, Florian [1 ]
机构
[1] Univ Med Greifswald, Innere Med C Hamatol & Onkol Stammzelltransplanta, Sauerbruchstr, D-17475 Greifswald, Germany
来源
ONKOLOGIE | 2022年 / 28卷 / 08期
关键词
Myeloproliferative neoplasms; risk-adapted therapy; Polycythemia vera; Thrombocythemia; essential; Primary myelofibrosis; Janus kinase inhibitors; INTERNATIONAL PROGNOSTIC SCORE; POLYCYTHEMIA-VERA; MYELOFIBROSIS; RUXOLITINIB; THROMBOSIS; EFFICACY; THERAPY; SAFETY;
D O I
10.1007/s00761-022-01191-y
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Classical chronic BCR::ABL1-negative myeloproliferative neoplasms include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). In recent years, there has been a significant improvement with respect to therapeutic options and strategies that include novel agents. Interferons, Janus kinase (JAK) inhibitors and combination treatment are among the clinical developments. An exact classification, diagnosis and risk stratification are crucial for optimizing the treatment strategy and personalized treatment.
引用
收藏
页码:721 / 730
页数:10
相关论文
共 50 条
  • [1] Innovative treatment strategies in myeloproliferative neoplasms
    Doehner, K.
    Stegelmann, F.
    Schlenk, R. F.
    ONKOLOGIE, 2011, 34 : 36 - 36
  • [2] Innovative treatment strategies in Myeloproliferative Neoplasms
    Doehner, K.
    Stegelmann, F.
    Griesshammer, M.
    Schlenk, R. F.
    ONKOLOGIE, 2012, 35 : 84 - 84
  • [3] Editorial: Novel Treatment Strategies for Myeloproliferative Neoplasms
    Lim, Ken-Hong
    Matsuura, Shinobu
    Xu, Bing
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [4] Extramedullary hematopoiesis in myeloproliferative neoplasms: Pathophysiology and treatment strategies
    Chernak, Brian J.
    Rampal, Raajit K.
    CELLULAR AND MOLECULAR ASPECTS OF MYELOPROLIFERATIVE NEOPLASMS - PT A, 2021, 365 : 97 - 116
  • [5] Comparison of Different Treatment Strategies for Blast-Phase Myeloproliferative Neoplasms
    Tokumori, Franco Castillo
    Al Ali, Najla
    Chan, Onyee
    Sallman, David
    Yun, Seongseok
    Sweet, Kendra
    Padron, Eric
    Lancet, Jeffrey
    Komrokji, Rami
    Kuykendall, Andrew T.
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2022, 22 (07): : E521 - E525
  • [6] Myeloproliferative Neoplasms: Molecular Pathophysiology, Essential Clinical Understanding, and Treatment Strategies
    Tefferi, Ayalew
    Vainchenker, William
    JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (05) : 573 - 582
  • [7] Current treatment of myeloproliferative neoplasms
    Al-Ali, Haifa Kathrin
    LEUKEMIA RESEARCH, 2018, 73 : S3 - S3
  • [8] CURRENT TREATMENT OF MYELOPROLIFERATIVE NEOPLASMS
    Al-Ali, Haifa Kathrin
    LEUKEMIA RESEARCH, 2016, 49 : S9 - S10
  • [9] Interferons in the treatment of myeloproliferative neoplasms
    Vachhani, Pankit
    Mascarenhas, John
    Bose, Prithviraj
    Hobbs, Gabriela
    Yacoub, Abdulraheem
    Palmer, Jeanne M.
    Gerds, Aaron T.
    Masarova, Lucia
    Kuykendall, Andrew T.
    Rampal, Raajit K.
    Mesa, Ruben
    Verstovsek, Srdan
    THERAPEUTIC ADVANCES IN HEMATOLOGY, 2024, 15
  • [10] CURRENT TREATMENT OF MYELOPROLIFERATIVE NEOPLASMS
    Al-Ali, Haifa Kathrin
    LEUKEMIA RESEARCH, 2017, 61 : S8 - S8