Late-onset Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-like Episodes (MELAS) Syndrome in a 63-year-old Patient

被引：5

作者：

Abdullah, Hassan ^{[1
,2
]}

Shah, Syed ^{[3
]}

Husain, Humza ^{[4
]}

Hassan, Furqan ^{[1
]}

Maqsood, Hamza ^{[3
]}

机构：

[1] Nishtar Med Univ, Med, Multan, Pakistan

[2] Univ Alabama Birmingham, Neurol, Birmingham, AL 35294 USA

[3] Nishtar Med Univ, Nishtar Hosp, Med, Multan, Pakistan

[4] Nishtar Med Univ, Internal Med, Multan, Pakistan

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2020年 / 12卷 / 04期

关键词：

melas; stroke; myopathy; encephalopathy; lactic acidosis; seizures; mri; mitochondrial dna mutation; ENCEPHALOPATHY; FEATURES; MYOPATHY;

D O I：

10.7759/cureus.7862

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) usually manifests in early life. Clinical hallmarks of the disease are mitochondrial myopathies, encephalopathy with stroke-like episodes, seizures, and lactic acidosis. It rarely manifests in late adulthood. Here we present the case of a 63-year-old female patient who developed recurrent stroke-like symptoms with typical resolving and remitting pattern of findings on imaging. Later on, it was confirmed as a case of MELAS upon genetic analysis.

引用

页数：7

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