An Epigenomic Road Map for Endoderm Development

被引:4
|
作者
Kaestner, Klaus H. [1 ,2 ]
机构
[1] Univ Penn, Dept Genet, Philadelphia, PA 19104 USA
[2] Univ Penn, Perelman Sch Med, Inst Diabet Obes & Metab, Philadelphia, PA 19104 USA
关键词
TRANSCRIPTION FACTORS; FOXA2; CELL;
D O I
10.1016/j.stem.2015.03.006
中图分类号
Q813 [细胞工程];
学科分类号
摘要
While studies of organ development have traditionally relied on model organisms, recent advances in embryonic stem cell (ESC) culture allow investigation of organogenesis in human cells. Wang et al. (2015) employ this system to map the dynamic enhancer landscape during ESC differentiation to the endoderm derivatives pancreas and liver.
引用
收藏
页码:343 / 344
页数:2
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