NMR determination of the absolute configuration of cyclic chiral alkenes

被引：19
|
作者：
Fukui, H
Fukushi, Y [1 ]
Tahara, S
机构：
[1] Hokkaido Univ, Fac Agr, Dept Appl Biosci, Kita Ku, Sapporo, Hokkaido 0608589, Japan
[2] Japan Sci & Technol Corp, CREST, Kawaguchi, Saitama 3320012, Japan
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 02期
关键词：
D O I：
10.1016/S0040-4039(98)02342-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
By the use of a new axially chiral reagent, 2'-methoxy-1,1'-binaphthalene-2-carbohydroximoyl chloride (MBCC), chiral cyclic alkenes were stereoselectively derivatized into 4,5-dihydroisoxazoles. NOEs were observed between the protons of the reagent moiety and those of the alkene moiety in cycloadducts. The absolute configuration of the original alkenes was unambiguously determined by the NOE; correlation. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：325 / 328
页数：4
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