Bacteria in tumors "hit the road'' together

被引:5
|
作者
Longmore, Gregory D. [1 ,2 ,3 ,4 ]
机构
[1] Washington Univ, Dept Med Oncol, St Louis, MO 63110 USA
[2] Washington Univ, Dept Cell Biol, St Louis, MO 63110 USA
[3] Washington Univ, Dept Physiol, St Louis, MO 63110 USA
[4] Washington Univ, ICCE Inst, St Louis, MO 63110 USA
关键词
CANCER; COLLAGEN;
D O I
10.1016/j.cell.2022.03.013
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Tumors contain bacteria, but the functional significance of this tumor microbiota is not appreciated. Fu et al. show that bacteria within breast tumor cells contribute to metastasis, in part, by enhancing tumor cell survival to mechanical fluid shear stress as would be found in the circulation.
引用
收藏
页码:1292 / +
页数:3
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