Ferrocene-Based Antibacterial Agents: Synthesis, Characterization, and Biological Evaluation of Metal (II) Complexes with Glycine-Derived Compounds

被引：1
|
作者：
Liu, Yuting [1 ]
Sun, Xiaoming [1 ]
Yin, Dawei [1 ]
机构：
[1] Shaanxi Univ Sci & Technol, Key Lab Auxiliary Chem & Technol Chem Ind, Minist Educ, Coll Chem & Chem Engn, Xian 710021, Peoples R China
来源：
ADVANCED MANUFACTURING SYSTEMS | 2011年 / 339卷
关键词：
ferrocene; glycine; Schiff bases; antibacterial; complex;
D O I：
10.4028/www.scientific.net/AMR.339.317
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
A series of Ferrocene Schiff bases derived from glycine and their cobalt (II), copper (II), nickel (II), and zinc (II) metal complexes have been synthesized and characterized by ER, 1H NMR, MS and elemental analysis, the results conformed well with expected structures. The synthesized ligands, along with their metal (II) complexes, were screened in vitro for their antibacterial activity against three Gram-negative (Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi) and two Gram-positive (Bacillus subtilis and Staphylococcus aureus) bacterial strains. The results showed that the metal (H) complexes are more potent in antibacterial activity against one or more species in comparison with those of uncomplexed ligands.
引用
收藏
页码：317 / 320
页数：4
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