Development of lentiviral vectors manufacturing process using a HEK293 producer cell line

被引:0
|
作者
Audy, A. [1 ,2 ]
Robert, M. A. [1 ,2 ]
Chahal, P. S. [2 ]
Gilbert, R. [2 ]
Gaillet, B. [1 ]
机构
[1] Univ Laval, Dept Chem Engn, Quebec City, PQ, Canada
[2] Natl Res Council Canada, Montreal, PQ, Canada
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
P385
引用
收藏
页码:A163 / A163
页数:1
相关论文
共 50 条
  • [1] Process Development of Lentiviral Vectors for Large Scale Production Using a HEK293 Producer Cell Line
    Audy, Alexandre
    Robert, Marc-Andre
    Chahal, Parminder
    Gilbert, Renald
    Gaillet, Bruno
    MOLECULAR THERAPY, 2016, 24 : S279 - S280
  • [2] Integrated Semi-Continuous Manufacturing of Lentiviral Vectors Using a HEK-293 Producer Cell Line
    Tran, Michelle Yen
    Dash, Shantoshini
    Yang, Zeyu
    Kamen, Amine A.
    PROCESSES, 2023, 11 (12)
  • [3] Production of Lentiviral Vectors Using a HEK-293 Producer Cell Line and Advanced Perfusion Processing
    Tran, Michelle Yen
    Kamen, Amine A.
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 10
  • [4] Continuous Perfusion with a Stable Producer HEK293 Cell Line for Scaling Up Lentiviral Vector Production
    Cattaneo, Maurizio
    Rodenbrock, Anja
    Lanthier, Stephane
    Burney, Elodie
    Spanjaard, Remco
    Manceur, Aziza
    MOLECULAR THERAPY, 2020, 28 (04) : 432 - 432
  • [5] SerLess: an adherent HEK293-derived producer cell line for manufacturing lentiviral vectors in the absence of animal-derived serum
    Fertin, M.
    Albo, C.
    Ramirez, J. C.
    HUMAN GENE THERAPY, 2019, 30 (11) : A41 - A41
  • [6] SerLESS, an Adherent HEK293-Derived Producer Cell Line for Manufacturing Lentiviral Vectors in Serum-Free Formulated Media
    Fertin, Marie
    Eugenia Yubero, Maria
    Albo, Carmen
    Carlos Ramirez, Juan
    MOLECULAR THERAPY, 2020, 28 (04) : 547 - 547
  • [7] Development of a Universal, GMP Ready, Clonal HEK293 Cell Line for the Manufacturing of Adeno Associated, Lenti, and Adenoviral Vectors
    Campbell, Marguerite
    Geosits, Kelly
    Ngan Trinh
    Umaer, Khan
    Tummala, Srivanya
    Burton, Thomas J.
    Krewson, Kaitlyn
    Russell, Ryann
    Tomkowicz, Brian
    MOLECULAR THERAPY, 2024, 32 (04) : 244 - 245
  • [8] HEK293 Cell Line as a Platform to Produce Recombinant Proteins and Viral Vectors
    Tan, Evan
    Chin, Cara Sze Hui
    Lim, Zhi Feng Sherman
    Ng, Say Kong
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2021, 9
  • [9] Continuous manufacturing of lentiviral vectors using a stable producer cell line in a fixed-bed bioreactor
    Stibbs, Dale J.
    Couto, Pedro Silva
    Takeuchi, Yasuhiro
    Rafiq, Qasim A.
    Jackson, Nigel B.
    Rayat, Andrea C. M. E.
    MOLECULAR THERAPY METHODS & CLINICAL DEVELOPMENT, 2024, 32 (01) : 1 - 11
  • [10] Development and improvement of a serum-free suspension process for the production of recombinant adenoviral vectors using HEK293 cells
    Tsao, YS
    Condon, R
    Schaefer, E
    Lio, P
    Liu, Z
    CYTOTECHNOLOGY, 2001, 37 (03) : 189 - 198