Single-nucleus RNA-seq and Spatial Transcriptomics of Archival Primary Pancreatic Ductal Adenocarcinoma Uncovers Multi-compartment Intratumoral Heterogeneity Associated with Neoadjuvant Chemoradiotherapy

被引:0
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作者
Hwang, W. [1 ]
Jagadeesh, K. [2 ]
Guo, J. A. [3 ]
Hoffman, H. I. [2 ]
Ashenberg, O. [2 ]
Drokhlyansky, E. [2 ]
Van Wittenberghe, N. [2 ]
Farhi, S. [2 ]
Schapiro, D. [2 ]
Rodriguez, C. [4 ]
Ciprani, D. [4 ]
Zollinger, D. [5 ]
Hong, T. S. [6 ]
Aguirre, A. [7 ]
Mino-Kenudson, M. [4 ]
Rozenblatt-Rosen, O. [2 ]
Fernandez-del Casti, C. [4 ]
Liss, A. [4 ]
Jacks, T. [8 ]
Regev, A. [2 ]
机构
[1] Massachusetts Gen Hosp, Harvard Radiat Oncol Program, Boston, MA 02114 USA
[2] Broad Inst, Cambridge, MA USA
[3] Broad Inst MIT & Harvard, Cambridge, MA 02142 USA
[4] Massachusetts Gen Hosp, Boston, MA 02114 USA
[5] NanoString Technol, Seattle, WA USA
[6] Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02114 USA
[7] Dana Farber Canc Inst, Boston, MA 02115 USA
[8] MIT, 77 Massachusetts Ave, Cambridge, MA 02139 USA
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2020年 / 108卷 / 03期
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
98
引用
收藏
页码:S48 / S49
页数:2
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