Benzannulated 6,5-Spiroketals from Donor-Acceptor Cyclopropanes

被引：16
|
作者：
Gai, Sinan [1 ]
Lucas, Nigel T. [1 ]
Hawkins, Bill C. [1 ]
机构：
[1] Univ Otago, Dept Chem, Dunedin 9054, New Zealand
来源：
ORGANIC LETTERS | 2019年 / 21卷 / 08期
关键词：
ASYMMETRIC-SYNTHESIS; EXPEDIENT SYNTHESIS; NATURAL-PRODUCTS; SPIROKETAL; ACID; CHROMONES; STRATEGIES; CHEMISTRY; INDOLES;
D O I：
10.1021/acs.orglett.9b00878
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A rapid and facile synthesis of benzannulated 6,5-spiroketals from vinyl 1,1-diacylcyclopropanes is reported. The method utilizes mild reaction conditions with good to excellent yields and high diastereoselectivity. This methodology was then used to construct the core of berkelic acid.
引用
收藏
页码：2872 / 2875
页数：4
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