Antenatal syphilis serology in pregnant women and follow-up of their infants in northern Italy

被引：19
|
作者：
Marangoni, A.
Moroni, A.
Tridapalli, E. [2 ]
Capretti, M. G. [2 ]
Farneti, G. [2 ]
Faldella, G. [2 ]
Antuono, A. D' [1 ,3 ]
Cevenini, R.
机构：
[1] Univ Bologna, S Orsola M Malpighi Hosp, Microbiol Sect, DMCSS, I-40138 Bologna, Italy
[2] Univ Bologna, Dept Prevent Paediat & Neonatol, I-40138 Bologna, Italy
[3] Univ Bologna, S Orsola M Malpighi Hosp, Dept Dermatol, I-40138 Bologna, Italy
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2008年 / 14卷 / 11期
关键词：
congenital syphilis; CSF; PolA PCR; serology; Treponema pallidum;
D O I：
10.1111/j.1469-0691.2008.02066.x
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Positive syphilis serology was noted in 119 (0.49%) of the 24 053 pregnant women delivering at St Orsola Hospital in Bologna, Italy, from November 2000 through July 2007. Six presumptive cases of congenital syphilis with IgM western blot positive results were found. Two infants had a positive cerebrospinal fluid (CSF) Venereal Disease Research Laboratory test result (one also had a positive CSF PCR result), another presented long-bone lesions, and the remaining three were preterm. These observations confirmed that antenatal syphilis screening facilitates treatment during pregnancy and offsets vertical transmission; moreover, the use of IgM western blot and careful CSF examination allowed the identification and treatment of high-risk newborns.
引用
收藏
页码：1065 / 1068
页数：4
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