Elimination of Cells from Patients with Different Subtypes of AML by Dual-Targeting Triplebody 33-16-123 (SPM-2)

被引：0

作者：

Braciak, T. ^{[1
]}

Fenn, N. ^{[2
]}

Wildenhain, S. ^{[2
]}

Schiller, C. ^{[2
]}

Roskopf, C. ^{[1
]}

Schubert, I. ^{[3
]}

Jacob, U. ^{[4
]}

Hopfner, K. P. ^{[2
]}

Aigner, M. ^{[5
]}

Mackensen, A. ^{[5
]}

Subklewe, M. ^{[6
]}

Spiekermann, K. ^{[6
]}

Fey, G. H.

Oduncu, F. ^{[1
]}

机构：

[1] Ludw Max Univ Munich, Med Klin & Poliklin 4, Sect Hematol Oncol, Munich, Germany

[2] Ludw Max Univ Munich, Genctr, Dept Biochem, Munich, Germany

[3] Friedr Alex Univ Erlangen Nuremberg, Dept Biol, Erlangen, Germany

[4] Westend Innovat Munich, Munich, Germany

[5] Univ Erlangen Nurnberg, Dept Internal Med 5, Hematol Oncol, Erlangen, Germany

[6] Ludw Max Univ Munich, Dept Internal Med 3, Hematol Oncol, Munich, Germany

来源：

ANNALS OF HEMATOLOGY | 2017年 / 96卷

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：S81 / S81

页数：1

共 8 条

[1] Efficient Elimination of Cells from Patients with Different AML Subtypes by Dual-Targeting Triplebody 33-16-123
Braciak, T.
Fenn, N.
Wildenhain, S.
Schiller, C.
Roskopf, C.
Schubert, I.
Jacob, U.
Hopfner, K. P.
Honegger, A.
Aigner, M.
Krause, S.
Macken-sen, A.
Subklewe, M.
Krupka, C.
Spiekermann, K.
Fey, G.
Oduncu, F. S.
ANNALS OF HEMATOLOGY, 2019, 98 : S58 - S58
[2] Dual-targeting triplebody 33-16-123 (SPM-2) mediates effective redirected lysis of primary blasts from patients with a broad range of AML subtypes in combination with natural killer cells
Braciak, Todd A.
Roskopf, Claudia C.
Wildenhain, Sarah
Fenn, Nadja C.
Schiller, Christian B.
Schubert, Ingo A.
Jacob, Uwe
Honegger, Annemarie
Krupka, Christina
Subklewe, Marion
Spiekermann, Karsten
Hopfner, Karl-Peter
Fey, Georg H.
Aigner, Michael
Krause, Stefan
Mackensen, Andreas
Oduncu, Fuat S.
ONCOIMMUNOLOGY, 2018, 7 (09):
[3] POTENT LYSIS OF AML BLASTS BY TRILYTE SPM-2 WITH DUAL-TARGETING OF CD33 AND CD123 IN COMBINATION WITH SUBSETS OF NK CELLS
Maier, C. P.
Heubach, F.
Herrmann, S.
Kuemmerle, P.
Braciak, T. A.
Fenn, N.
Schele, A.
Schubert, I.
Hopfner, K. P.
Krupka, C.
Subklewe, M.
Aigner, M.
Mackensen, A.
Lengerke, C.
Fey, G. H.
Peipp, M.
Lang, P.
Oduncu, F.
ANNALS OF HEMATOLOGY, 2023, 102 (SUPPL 1) : S65 - S65
[4] Effective lysis of MOLM-13 and AML blasts by triplebody spm-2 (cd123-16-33) in combination with subsets of nk cells
Maier, C-P.
Heubach, F.
Herrmann, S.
Kummerle, P.
Arendt, A-M.
Rabsteyn, A.
Fey, G. H.
Peipp, M.
Lengerke, C.
Bethge, W.
Handgretinger, R.
Lang, P.
BONE MARROW TRANSPLANTATION, 2022, 57 (SUPPL 1) : 336 - 337
[5] NK cells from an AML patient have recovered in remission and reached comparable cytolytic activity to that of a healthy monozygotic twin mediated by the single-chain triplebody SPM-2
Braciak, Todd A.
Wildenhain, Sarah
Roskopf, Claudia C.
Schubert, Ingo A.
Fey, Georg H.
Jacob, Uwe
Hopfner, Karl-Peter
Oduncu, Fuat S.
JOURNAL OF TRANSLATIONAL MEDICINE, 2013, 11
[6] Dual-Targeting CD33/CD123 NANOBODY ® T Cell Engager Targeting Leukemia Blasts and Stem/Progenitor Cells in Relapsed AML
Zeng, Zhihong
Roobrouck, Annelies
Deschamps, Geert
Bonnevaux, Helene
Guerif, Stephane
De Brabandere, Veronique
Celine, Amara
Jonckheere, Eline
Virone-Oddos, Angela
Chiron, Marielle
Dullaers, Melissa
Konopleva, Marina Y.
BLOOD, 2023, 142
[7] NK cells from an AML patient have recovered in remission and reached comparable cytolytic activity to that of a healthy monozygotic twin mediated by the single-chain triplebody SPM-2
Todd A Braciak
Sarah Wildenhain
Claudia C Roskopf
Ingo A Schubert
Georg H Fey
Uwe Jacob
Karl-Peter Hopfner
Fuat S Oduncu
Journal of Translational Medicine, 11
[8] A TRISPECIFIC ANTIBODY DERIVATIVE DIRECTED AGAINST CD123 AND CD33 MEDIATES EFFECTIVE ELIMINATION OF AML CELLS BY DUAL TARGETING
Kuegler, Markus
Stein, Christoph
Kellner, Christian
Mentz, Kristin
Saul, Domenica
Schwenkert, Michael
Schubert, Ingo
Singer, Heiko
Oduncu, Fuat
Stockmeyer, Bernhard
Mackensen, Andreas
Hillen, Wolfgang
Fey, Georg H.
ANNALS OF HEMATOLOGY, 2011, 90 : S1 - S1

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