Elevated levels of β6 integrin and alpha smooth actin positive microparticles in nasal lavage fluid in chronic rhinosinusitis with nasal polyps: a potential biomarker of epithelial-mesenchymal transition in the pathophysiology of polyp recurrence

被引：0

作者：

Takahashi, Toru ^{[1
]}

Kato, Atsushi ^{[1
]}

Berdnikovs, Sergejs ^{[1
]}

Stevens, Whitney W. ^{[1
]}

Suh, Lydia A. ^{[1
]}

Norton, James E. ^{[1
]}

Carter, Roderick G. ^{[1
]}

Harris, Kathleen E. ^{[1
]}

Peters, Anju T. ^{[1
]}

Hulse, Kathryn E. ^{[1
]}

Grammer, Leslie C. ^{[1
]}

Welch, Kevin C. ^{[2
]}

Shintani-Smith, Stephanie ^{[2
]}

Tan, Bruce K. ^{[2
]}

Conley, David B. ^{[2
]}

Kern, Robert C. ^{[2
]}

Schleimer, Robert P. ^{[1
]}

机构：

[1] Northwestern Univ, Dept Med, Feinberg Sch Med, Div Allergy & Immunol, Chicago, IL 60611 USA

[2] Northwestern Univ, Feinberg Sch Med, Dept Otolaryngol, Chicago, IL 60611 USA

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2018年 / 141卷 / 02期

关键词：

D O I：

10.1016/j.jaci.2017.12.210

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

208

引用

页码：AB66 / AB66

页数：1

共 5 条

[1] Detection of microparticles in nasal lavage fluid that express both integrin β6 and a marker of epithelial-mesenchymal transition (either alpha-smooth muscle actin or Snail) is useful for the identification of severe chronic rhinosinusitis
Takahashi, Toru
Kato, Atsushi
Berdnikovs, Sergejs
Suh, Lydia A.
Norton, James E.
Carter, Roderick G.
Harris, Kathleen E.
Stevens, Whitney W.
Peters, Anju T.
Grammer, Leslie C.
Welch, Kevin C.
Shintani-Smith, Stephanie
Conley, David B.
Kern, Robert C.
Schleimer, Robert P.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2019, 143 (02) : AB212 - AB212
[2] CD109 identified in circulating proteomics mitigates postoperative recurrence in chronic rhinosinusitis with nasal polyps by suppressing TGF-131-induced epithelial-mesenchymal transition
Gao, Ru
Chen, Yu
Liu, Huihong
Ye, Maoyu
Chu, Ling
Wang, Tiansheng
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 130
[3] Inhibition of IL-4/STAT6/IRF4 signaling reduces the epithelial-mesenchymal transition in eosinophilic chronic rhinosinusitis with nasal polyps
Chen, Jingcai
Chen, Shan
Gong, Guoqing
Yang, Fan
Chen, Jianjun
Wang, Yanjun
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 121
[4] E3 ubiquitin ligase NEDD4L inhibits epithelial-mesenchymal transition by suppressing the β-catenin/HIF-1α positive feedback loop in chronic rhinosinusitis with nasal polyps
Si-yuan Chen
Pei-qiang Liu
Dan-xue Qin
Hao Lv
Hui-qin Zhou
Yu Xu
Acta Pharmacologica Sinica, 2024, 45 : 831 - 843
[5] E3 ubiquitin ligase NEDD4L inhibits epithelial-mesenchymal transition by suppressing the β-catenin/HIF-1α positive feedback loop in chronic rhinosinusitis with nasal polyps
Chen, Si-yuan
Liu, Pei-qiang
Qin, Dan-xue
Lv, Hao
Zhou, Hui-qin
Xu, Yu
ACTA PHARMACOLOGICA SINICA, 2024, 45 (04) : 831 - 843

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