anti-inflammatory;
antioxidants;
complementary and alternative medicine (CAM);
exercise;
integrative medicine;
over-the-counter (OTC);
Parkinson disease;
ACETYL-L-CARNITINE;
PROTECTS DOPAMINERGIC-NEURONS;
ALPHA-LIPOIC ACID;
OXIDATIVE STRESS;
VITAMIN-C;
CEREBROSPINAL-FLUID;
N-ACETYLCYSTEINE;
MOTOR DEFICITS;
IN-VITRO;
MODEL;
D O I:
10.1097/TGR.0000000000000278
中图分类号:
R4 [临床医学];
R592 [老年病学];
学科分类号:
1002 ;
100203 ;
100602 ;
摘要:
Parkinson disease (PD) is the second most common neurodegenerative disorder with approximately 60 000 newly diagnosed patients yearly in the United States. PD is traditionally described as a motor system condition, although numerous nonmotor symptoms exist, and typically manifest within elderly patients. The hallmark pathogenesis of PD is the loss of dopaminergic neurons within the substantia nigra region. This leads to a traditional treatment goal of dopamine replacement. We outline an integrative medicine and health strategy for PD that utilizes not only traditional but also nontraditional therapeutic approaches. This strategy supports the neuronal microenvironment and restorative health of both the brain and the body.
机构:
Dongguk Univ, Grad Sch, Coll Korean Med, Dept Prevent Med, Seoul, South KoreaDongguk Univ, Grad Sch, Coll Korean Med, Dept Prevent Med, Seoul, South Korea
机构:
Acad Consortium Integrat Med & Hlth, 6728 Old McLean Village Dr, Mclean, VA 22101 USAAcad Consortium Integrat Med & Hlth, 6728 Old McLean Village Dr, Mclean, VA 22101 USA
机构:
Massachusetts Gen Hosp, Div Gen Internal Med, Benson Henry Inst Mind Body Med, 151 Merrimac St,4th Floor, Boston, MA 02114 USAMassachusetts Gen Hosp, Div Gen Internal Med, Benson Henry Inst Mind Body Med, 151 Merrimac St,4th Floor, Boston, MA 02114 USA
Dossett, Michelle L.
Cohen, Ezra M.
论文数: 0引用数: 0
h-index: 0
机构:
Boston Childrens Hosp, Dept Rheumatol, Div Immunol, 300 Longwood Ave, Boston, MA 02115 USAMassachusetts Gen Hosp, Div Gen Internal Med, Benson Henry Inst Mind Body Med, 151 Merrimac St,4th Floor, Boston, MA 02114 USA
Cohen, Ezra M.
Cohen, Jonah
论文数: 0引用数: 0
h-index: 0
机构:
Beth Israel Deaconess Med Ctr, Div Gastroenterol & Hepatol, 330 Brookline Ave,Dana 501, Boston, MA 02215 USAMassachusetts Gen Hosp, Div Gen Internal Med, Benson Henry Inst Mind Body Med, 151 Merrimac St,4th Floor, Boston, MA 02114 USA
机构:
Loyola Univ, Dept Family Med, Chicago Stritch Sch Med, Maywood, IL 60153 USA
Loyola Univ Hlth Syst, Maywood, IL 60153 USALoyola Univ, Dept Family Med, Chicago Stritch Sch Med, Maywood, IL 60153 USA
Michelfelder, Aaron J.
Lee, Kit C.
论文数: 0引用数: 0
h-index: 0
机构:
Loyola Univ, Dept Family Med, Chicago Stritch Sch Med, Maywood, IL 60153 USA
Loyola Univ Hlth Syst, Maywood, IL 60153 USALoyola Univ, Dept Family Med, Chicago Stritch Sch Med, Maywood, IL 60153 USA
Lee, Kit C.
Bading, Eva M.
论文数: 0引用数: 0
h-index: 0
机构:
Loyola Univ, Dept Family Med, Chicago Stritch Sch Med, Maywood, IL 60153 USA
Loyola Univ Hlth Syst, Maywood, IL 60153 USALoyola Univ, Dept Family Med, Chicago Stritch Sch Med, Maywood, IL 60153 USA