Efficient solvent-free synthesis of tertiary propargylic alcohols from arylacetylenes and ketones promoted by tert-BuOK

被引：22
|
作者：
Chen, Shufeng [1 ]
Yuan, Fang [1 ]
Zhao, Haiying [1 ]
Li, Baoguo [1 ]
机构：
[1] Inner Mongolia Univ, Coll Chem & Chem Engn, Hohhot 010021, Peoples R China
来源：
RESEARCH ON CHEMICAL INTERMEDIATES | 2013年 / 39卷 / 06期
基金：
中国国家自然科学基金;
关键词：
Solvent-free; Tertiary propargylic alcohols; Alkynylation; Potassium tert-butoxide; ASYMMETRIC ALKYNYLATION; CATALYTIC ALKYNYLATION; ALDEHYDES; ACETYLIDES; ACETYLENES; HYDROXIDE; ADDITIONS; ALKYNES;
D O I：
10.1007/s11164-012-0765-9
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A mild and efficient method for the alkynylation of arylacetylenes with ketones promoted by tert-BuOK under solvent-free conditions was developed. The present green synthesis was applicable to many kinds of aromatic and aliphatic ketones providing good to excellent yields of tertiary propargylic alcohols. A mild and efficient method for the alkynylation of arylacetylenes with ketones promoted by tert-BuOK under solvent-free conditions was developed. The present green synthesis was applicable to many kinds of aromatic and aliphatic ketones providing good to excellent yields of tertiary propargylic alcohols.
引用
收藏
页码：2391 / 2399
页数：9
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