Single-Cell Network Profiling (SCNP)-Based Classifier to Predict Response to Induction Therapy in Elderly Patients with Acute Myeloid Leukemia (AML): Validation in Two Independent Sample Sets From ECOG and SWOG Trials

被引：1

作者：

Cesano, Alessandra ^{[1
]}

Willman, Cheryl L. ^{[2
]}

Kopecky, Kenneth J. ^{[3
]}

Gayko, Urte ^{[1
]}

Putta, Santosh ^{[1
]}

Louie, Brent ^{[1
]}

Westfall, Matt ^{[1
]}

Purvis, Norman ^{[1
]}

Spellmeyer, David ^{[1
]}

Marimpietri, Carol ^{[1
]}

Hackett, James ^{[1
]}

Shi, Jing ^{[1
]}

Paietta, Elisabeth ^{[4
]}

Tallman, Martin S. ^{[5
]}

Cripe, Larry D. ^{[6
]}

Atwater, Susan K. ^{[7
]}

Appelbaum, Frederick R. ^{[8
]}

Radich, Jerald P. ^{[8
]}

机构：

[1] Nodality Inc, San Francisco, CA USA

[2] Univ New Mexico, Ctr Canc, Albuquerque, NM 87131 USA

[3] Fred Hutchinson Canc Res Ctr, SWOG Stat Ctr, Seattle, WA 98104 USA

[4] Montefiore Med Ctr, Bronx, NY 10467 USA

[5] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA

[6] Indiana Univ, Ctr Canc, Indianapolis, IN 46204 USA

[7] Stanford Univ, Dept Pathol, Palo Alto, CA 94304 USA

[8] Fred Hutchinson Canc Res Ctr, Div Clin Res, Seattle, WA 98104 USA

来源：

BLOOD | 2012年 / 120卷 / 21期

关键词：

D O I：

10.1182/blood.V120.21.2489.2489

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

2489

引用

页数：2

共 10 条

[1] Single Cell Network Profiling (SCNP)-Based Classifier to Predict Response to Induction Therapy in Pediatric Patients with De Novo Acute Myeloid Leukemia (AML): Validation Study Results
Lacayo, Norman J.
Alonzo, Todd A.
Gayko, Urte
Westfall, Matt
Purvis, Norman
Putta, Santosh
Hackett, James
Cohen, Aileen Cleary
Gerbing, Robert B.
Dahl, Gary V.
Gamis, Alan S.
Meshinchi, Soheil
BLOOD, 2011, 118 (21) : 1512 - 1513
[2] Using Single-cell Network Profiling (SCNP) Signatures to Predict Response to Induction Therapy and Relapse Risk in Pediatric Patients With Acute Myeloid Leukemia (AML)
Cesano, A.
Westfall, M.
Rosen, D.
Louie, B.
Meshinchi, S.
Alonzo, T.
Arceci, R.
Ravindranath, Y.
Dahl, G.
Lacayo, N.
EUROPEAN JOURNAL OF CANCER, 2011, 47 : S137 - S137
[3] Single-Cell Network Profiliing (SCNP) Signatures Independently Predict Response to Induction Therapy In Older Patients with Acute Myeloid Leukemia (AML)
Cesano, Alessandra
Putta, Santosh
Gayko, Urte
Hackett, James
Rosen, David B.
Cripe, Larry
Sun, Zhuoxin
Uno, Hajime
Litzow, Mark R.
Tallman, Martin S.
Paietta, Elisabeth
BLOOD, 2010, 116 (21) : 1110 - 1111
[4] Development and validation of a single-cell network profiling assay-based classifier to predict response to induction therapy in paediatric patients with de novo acute myeloid leukaemia: a report from the Children's Oncology Group
Lacayo, Norman J.
Alonzo, Todd A.
Gayko, Urte
Rosen, David B.
Westfall, Matt
Purvis, Norman
Putta, Santosh
Louie, Brent
Hackett, James
Cohen, Aileen Cleary
Cesano, Alessandra
Gerbing, Robert
Ravindranath, Yaddanapudi
Dahl, Gary V.
Gamis, Alan
Meshinchi, Soheil
BRITISH JOURNAL OF HAEMATOLOGY, 2013, 162 (02) : 250 - 262
[5] Cell Signaling-Based Classifier Predicts Response to Induction Therapy in Elderly Patients with Acute Myeloid Leukemia
Cesano, Alessandra
Willman, Cheryl L.
Kopecky, Kenneth J.
Gayko, Urte
Putta, Santosh
Louie, Brent
Wesdall, Matt
Purvis, Norman
Spellmeyer, David C.
Marimpietri, Carol
Cohen, Aileen C.
Hackett, James
Shi, Jing
Walker, Michael G.
Sun, Zhuoxin
Paietta, Elisabeth
Tallman, Martin S.
Cripe, Larry D.
Atwater, Susan
Appelbaum, Frederick R.
Radich, Jerald P.
PLOS ONE, 2015, 10 (04):
[6] Single Cell Network Profiling (SCNP) Signatures Predict Response to Induction Therapy and Relapse Risk In Pediatric Patients with Acute Myeloid Leukemia: Children's Oncology Group (COG) Study POG-9421
Lacayo, Norman J.
Cohen, Aileen
Westfall, Matt
Lackey, Alan
Xin, Xiaohua
Gayko, Urte
Putta, Santosh
Meshinch, Soheil
Raimondi, Susana C.
Alonzo, Todd A.
Arceci, Robert J.
Ravindranath, Yaddanapudi
Dahl, Gary Van Houten
Cesano, Alessandra
BLOOD, 2010, 116 (21) : 420 - 421
[7] Single Cell Network Profiling (SCNP) Functionally Characterizes FLT3 Pathway Deregulation in Non-M3 Acute Myeloid Leukemia (AML) and Provides Prognostic Value Independent From Mutational Status
Cesano, Alessandra
Putta, Santosh
Mathi, Kavita
Rosen, David B.
Gayko, Urte
Hawtin, Rachael E.
Cripe, Larry D.
Sun, Zhuoxin
Tallman, Martin S.
Paietta, Elisabeth
BLOOD, 2011, 118 (21) : 1075 - 1076
[8] Single-cell profiling of acute myeloid leukemia (AML) and its microenvironment reveals a CD8 continuum and adaptable T cell plasticity in response to PD-1 blockade-based therapy.
Hao, Dapeng
Tomczak, Katarzyna
Barrodia, Praveen
Im, Jin Seon
Reville, Patrick K.
Al-Atrash, Gheath
Ning, Jing
Ding, Maomao
Mathews, Jairo T.
Little, Latasha
Zhang, Jianhua
Basu, Sreyashi
Konopleva, Marina
Garcia-Manero, Guillermo
Green, Michael R.
Sharma, Padmanee
Allison, James P.
Kornblau, Steven M.
Rai, Kunal
Wang, Linghua
Daver, Naval
Futreal, Andrew
CANCER IMMUNOLOGY RESEARCH, 2021, 9 (02)
[9] SINGLE CELL PROFILING OF ACUTE MYELOID LEUKEMIA (AML) AND ITS MICROENVIRONMENT REVEALS A CD8 CONTINUUM AND ADAPTABLE T CELL PLASTICITY IN RESPONSE TO PD-1 BLOCKADE-BASED THERAPY
Abbas, Hussein
Hao, Dapeng
Tomczak, Katarzyna
Barrodia, Praveen
Im, Jin Seon
Reville, Patrick
Alaniz, Zoe
Wang, Wei
Wang, Ruiping
Wang, Feng
Al-Atrash, Gheath
Takahashi, Koichi
Ning, Jing
Ding, Maomao
Matthews, Jairo
Little, Latasha
Zhang, Jianhua
Basu, Sreyashi
Konopleva, Marina
Garcia-Manero, Guillermo
Green, Michael
Sharma, Padmanee
Allison, James
Kornblau, Steven
Rai, Kunal
Wang, Linghua
Daver, Naval
Futreal, Andrew
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 : A445 - A446
[10] Polyfunctionality determined by single-cell proteomics of bone marrow-derived CD4 T cells from patients with acute myeloid leukemia identifies patients responding to anti-PD-1-based therapy and discovers profound T cell defect in mutant TP53 disease
Daver, Naval
Kantarjian, Hagop
Mackay, Sean
Flynn, Brianna
Basu, Sreyashi
Garcia-Manero, Guillermo
Alfayez, Mansour
Konopleva, Marina
Matthews, Jairo
Kornblau, Steven
Jabbour, Ellias
Zhou, Jing
Andreeff, Michael
CANCER RESEARCH, 2019, 79 (13)

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