Tin-free radical chemistry: intramolecular addition of alkyl radicals to aldehydes and ketones

被引：56
|
作者：
Devin, P [1 ]
Fensterbank, L [1 ]
Malacria, M [1 ]
机构：
[1] Univ Paris 06, CNRS, Lab Chim Organ Synth, F-75252 Paris 05, France
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 30期
关键词：
D O I：
10.1016/S0040-4039(99)01072-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The radical cyclization of several omega-iodoaldehydes and a ketone can be accomplished without the use of tributyltin hydride. Triethylborane in presence of oxygen or light from a sun lamp can serve as a radical initiator and terminator. In these conditions, a 5-exo-trig cyclization on an aldehyde is faster than on an alkene. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.
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收藏
页码：5511 / 5514
页数：4
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