Palladium-catalyzed arylation/cyclization/desulfonation cascades toward 4-aryl quinolin-2(1H)-ones with diaryliodonium salts

被引：7
|
作者：
Han, Jianwei [1 ,2 ]
Wu, Xunshen [1 ]
Zhang, Zhiang [1 ]
Wang, Limin [1 ]
机构：
[1] East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Key Lab Adv Mat, 130 Meilong Road, Shanghai 200237, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai Hong Kong Joint Lab Chem Synth, 345 Ling Ling Rd, Shanghai 200032, Peoples R China
来源：
TETRAHEDRON LETTERS | 2017年 / 58卷 / 35期
关键词：
Arylation; Cyclization; Diaryliodonium salt; 4-Aryl quinolin-2(1H)-ones; HECK REACTION; INTRAMOLECULAR CYCLIZATION; 2-QUINOLINONES; 4-ARYL-2-QUINOLONES; ACTIVATION; ROUTE; ACIDS; AMIDATION;
D O I：
10.1016/j.tetlet.2017.07.065
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium-catalyzed cascades of arylation/cyclization/desulfonation of ortho-aminocinnamate esters by using diaryliodonium salts afforded a wide range of 4-aryl quinolin-2(1H)-ones. As such, the desired 4-aryl quinolin-2(1H)-ones with potential biological activity has been synthesized in the yields of 34-96%. (C) 2017 Published by Elsevier Ltd.
引用
收藏
页码：3433 / 3436
页数：4
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