Symptomatic Chikungunya Virus Infection and Pregnancy Outcomes: A Nested Case-Control Study in French Guiana

被引:6
|
作者
Basurko, Celia [1 ]
Hcini, Najeh [2 ]
Demar, Magalie [3 ]
Abboud, Philippe [4 ]
Nacher, Mathieu [1 ]
Carles, Gabriel [2 ]
Lambert, Veronique [2 ]
Matheus, Severine [5 ,6 ]
机构
[1] Ctr Hosp Cayenne, CIC Inserm 1424, Ctr Invest Clin Antilles Guyane, Av Flamboyants, Cayenne 97300, French Guiana
[2] West French Guiana Hosp Ctr, Dept Obstet & Gynaecol, St Laurent Du Maroni 97320, French Guiana
[3] Ctr Hosp Cayenne, Lab Hosp Univ Parasitol Mycol, Cayenne 97300, French Guiana
[4] Ctr Hosp Cayenne, Infect & Trop Dis Dept, Cayenne 97300, French Guiana
[5] Cayenne Gen Hosp, Intens Care Unit, Cayenne 97300, French Guiana
[6] Inst Pasteur, Natl Reference Ctr Arboviruses, Lab Virol, Cayenne 97300, French Guiana
来源
VIRUSES-BASEL | 2022年 / 14卷 / 12期
关键词
Chikungunya virus; French Guiana; neonatal outcomes; pregnancy; pregnancy outcomes; DIAGNOSIS; COLOMBIA; OUTBREAK;
D O I
10.3390/v14122705
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
During the Chikungunya epidemic in the Caribbean and Latin America, pregnant women were affected by the virus in French Guiana. The question of the impact of the virus on pregnancy was raised because of the lack of scientific consensus and published data in the region. Thus, during the Chikungunya outbreak in French Guiana, a comparative study was set up using a cohort of pregnant women. The objective was to compare pregnancy and neonatal outcomes between pregnant women with Chikungunya virus (CHIKV) infection and pregnant women without CHIKV. Of 653 mothers included in the cohort, 246 mothers were included in the case-control study: 73 had CHIKV fever during pregnancy and 173 had neither fever nor CHIKV during pregnancy. The study did not observe any severe clinical presentation of CHIKV in the participating women. There were no intensive care unit admissions. In addition, the study showed no significant difference between the two groups with regard to pregnancy complications. However, the results showed a potential excess risk of neonatal ICU admission of the newborn when the maternal infection occurred within 7 days before delivery. These results suggest that special attention should be paid to neonates whose mothers were infected with CHIKV shortly before delivery.
引用
收藏
页数:10
相关论文
共 50 条
  • [1] Discriminating Tonate Virus from Dengue Virus Infection: A Matched Case-Control Study in French Guiana, 2003-2016
    Mutricy, Remi
    Djossou, Felix
    Matheus, Severine
    Lorenzi-Martinez, Enguerrane
    De Laval, Franck
    Demar, Magalie
    Nacher, Mathieu
    Rousset, Dominique
    Epelboin, Loic
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2020, 102 (01): : 195 - 201
  • [2] Association of gestational anemia with pregnancy conditions and outcomes: A nested case-control study
    Sun, Yin
    Shen, Zhong-Zhou
    Huang, Fei-Ling
    Jiang, Yu
    Wang, Ya-Wen
    Zhang, Su-Han
    Ma, Shuai
    Liu, Jun-Tao
    Zhan, Yong-Le
    Lin, Hang
    Chen, Yun-Li
    Shi, Ying-Jie
    Ma, Liang-Kun
    WORLD JOURNAL OF CLINICAL CASES, 2021, 9 (27) : 8008 - 8019
  • [3] Association of gestational anemia with pregnancy conditions and outcomes: A nested case-control study
    Yin Sun
    Zhong-Zhou Shen
    Fei-Ling Huang
    Yu Jiang
    Ya-Wen Wang
    Su-Han Zhang
    Shuai Ma
    Jun-Tao Liu
    Yong-Le Zhan
    Hang Lin
    Yun-Li Chen
    Ying-Jie Shi
    Liang-Kun Ma
    World Journal of Clinical Cases, 2021, 9 (27) : 8008 - 8019
  • [4] Neonatal outcomes related to maternal SARS-CoV-2 infection in French Guiana: A case-control study.
    Elenga, N.
    Wandji, M. -j.
    Siban, J.
    Nacher, M.
    Demar, M.
    JOURNAL OF INFECTION AND PUBLIC HEALTH, 2022, 15 (07) : 746 - 751
  • [5] Atypical and severe manifestations of chikungunya virus infection in French Guiana: A hospital-based study
    Bonifay, Timothee
    Prince, Christelle
    Neyra, Clarisse
    Demar, Magalie
    Rousset, Dominique
    Kallel, Hatem
    Nacher, Mathieu
    Djossou, Felix
    Epelboin, Loic
    PLOS ONE, 2018, 13 (12):
  • [6] Epstein-Barr Virus infection and gastric cancer in Korea: a nested case-control study
    Yoo, Keun-Young
    Kim, Yeonju
    Gwack, Jin
    Kang, Daehee
    Hong, Yun-Chul
    CANCER RESEARCH, 2006, 66 (08)
  • [7] Analysis of secondary outcomes in nested case-control study designs
    Kim, Ryung S.
    Kaplan, Robert C.
    STATISTICS IN MEDICINE, 2014, 33 (24) : 4215 - 4226
  • [8] Outcomes of saddle pulmonary embolism: a nested case-control study
    Gandara, E.
    Bose, G.
    Erkens, P.
    Rodgers, M.
    Carrier, M.
    Wells, P.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2011, 9 (04) : 867 - 869
  • [9] Analysis on the outcomes of hepatitis B virus perinatal vertical transmission: nested case-control study
    Lv, Nan
    Chu, Xiao-Dan
    Sun, Yu-Hong
    Zhao, Shu-Yu
    Li, Pei-Ling
    Chen, Xuan
    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2014, 26 (11) : 1286 - 1291
  • [10] Associations between domestic violence and poor pregnancy outcomes in taiwanese women: a nested case-control study
    Lin, Chia-Ling
    Sun, Jui-Chiung
    Lin, Chun-Ping
    Chung, Chi-Hsiang
    Chien, Wu-Chien
    BMC WOMENS HEALTH, 2023, 23 (01)