Aripiprazole: a novel atypical antipsychotic acts as stabilizer of the dopamine system

被引：0
|
作者：
Klein, N [1 ]
Wallner, H [1 ]
Kasper, S [1 ]
机构：
[1] Klin Abt Allgemeine Psychiat, A-1090 Vienna, Austria
来源：
PSYCHOPHARMAKOTHERAPIE | 2006年 / 13卷 / 02期
关键词：
aripiprazole; dopamine stabilizer; partial agonist; schizophrenia; bipolar disorder;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Aripiprazole is a new atypical antipsychotic with a unique mechanism of action. It is a partial agonist to the D-2 receptor and therefore acts as stabilizer of the dopaminergic system. Aripiprazole has been shown to have good efficacy on (a) treating positive and negative symptoms of schizophrenia and (b) treating bipolar disorders. Furthermore, aripiprazole has a favourable adverse event profile, which in many cases does not differ from placebo.
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页码：49 / +
页数：6
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