Rapid, noninvasive diagnosis of visceral Leishmaniasis in India: Comparison of two immunochromatographic strip tests for detection of anti-K39 antibody

被引：66
|
作者：
Sundar, S
Maurya, R
Singh, RK
Bharti, K
Chakravarty, J
Parekh, A
Rai, M
Kumar, K
Murray, HW
机构：
[1] Banaras Hindu Univ, Inst Med Sci, Dept Med, Kala Azar Med Res Ctr, Varanasi 221005, Uttar Pradesh, India
[2] Cornell Univ, Weill Med Coll, Dept Med, New York, NY 10021 USA
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2006年 / 44卷 / 01期
关键词：
D O I：
10.1128/JCM.44.1.251-253.2006
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Used with blood or serum, a new anti-K39 antibody immunochromatographic strip test (IT-Leish; DiaMed AG) proved sensitive (range, 99 to 100%) and specific (range, 95 to 100%) for the noninvasive serodiagnosis of visceral leishmaniasis in India. Used with serum, the IT-Leish test and the existing Kalazar Detect test (InBios International, Inc.) yielded comparable results for symptomatic infection and identified apparent subclinical infection in 15 to 32% of healthy residents in a region where visceral leishmaniasis is highly endemic.
引用
收藏
页码：251 / 253
页数：3
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