Nanoscale surface modification of plastic substrates for advanced tissue engineering applications

被引:1
|
作者
Donkov, N. [1 ]
Safonov, V. [2 ]
Zykova, A. [2 ]
Smolik, J. [3 ]
Rogovska, R.
Goltsev, A. [4 ]
Dubrava, T. [4 ]
Rossokha, I. [4 ]
Georgieva, V. [5 ]
机构
[1] Bulgarian Acad Sci, Emil Djakov Inst Elect, Sofia, Bulgaria
[2] Kharkov Inst Phys & Technol, NSC, Kharkov, Ukraine
[3] Inst Sustainable Technol, NRC, Radom, Poland
[4] Inst Problems Cryobiol & Cryomed NASU, Kharkov, Ukraine
[5] Bulgarian Acad Sci, Georgi Nadjakov Inst Solid State Phys, Sofia 1784, Bulgaria
关键词
MESENCHYMAL STEM-CELLS;
D O I
10.1088/1742-6596/398/1/012031
中图分类号
O59 [应用物理学];
学科分类号
摘要
Modified surface properties such as composition, nano roughness, wettability have effect on the most important processes at biomaterial interface. The research of stem cells (MSCs) adhesive potential, morphology, phenotypical characteristics on oxide coated and plastic substrate with different surface parameters was made. The oxide coatings deposition on plastic substrates shifts the surface properties at the more hydrophilic region and results in next positive cell/biomaterial response in vitro tests. The MSCs marker number increases on the oxide nano structural surface of plastic substrates.
引用
收藏
页数:5
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