Ultrasound-assisted synthesis and antimicrobial activity of tetrazole-based pyrazole and pyrimidine derivatives

被引：13

作者：

Dofe, Vidya S. ^{[1
]}

Sarkate, Aniket P. ^{[2
]}

Shaikh, Zarina M. ^{[3
]}

Gill, Charansingh H. ^{[1
]}

机构：

[1] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem, Aurangabad 431004, Maharashtra, India

[2] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem Technol, Aurangabad 431004, Maharashtra, India

[3] Maulana Azad Coll Arts Sci & Commerce, Dept Microbiol, Aurangabad 431001, Maharashtra, India

来源：

HETEROCYCLIC COMMUNICATIONS | 2018年 / 24卷 / 01期

关键词：

antimicrobial; pyrazole; pyrimidine; tetrazole; ultrasound; AGENTS; INHIBITORS; DESIGN; SERIES; SAR;

D O I：

10.1515/hc-2017-0067

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New tetrazole-based pyrazole and pyrimidine derivatives were synthesized by an ultrasound irradiation method. All compounds were characterized by infrared spectroscopy (IR), H-1 nuclear magnetic resonance (NMR), C-13 NMR, mass spectrometry (MS) and elemental analysis and assessed in vitro for their efficacy as antimicrobial agents against four bacteria (Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa) and two fungi (Candida albicans, Aspergillus niger). Compounds 8a, 8e, 9a, 9b and 9e show potent activity against the tested strains compared to the reference drugs chloramphenicol and clotrimazole.

引用

页码：59 / 65

页数：7

共 50 条

[1] Ultrasound-assisted Synthesis of Novel Pyrazole and Pyrimidine Derivatives as Antimicrobial Agents
Dofe, Vidya S.
Sarkate, Aniket P.
Shaikh, Zarina M.
Jadhav, Chetan K.
Nipte, Amol S.
Gill, Charansingh H.
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2018, 55 (03) : 756 - 762
[2] Synthesis and Evaluation of Tetrazole-Based Hydrazone Derivatives Bearing a Pyridine Moiety as Antimicrobial Agents
Ozdemir, Ahmet
Altintop, Mehlika Dilek
Sever, Belgin
Canturk, Zerrin
Kaplancikli, Zafer Asim
LETTERS IN DRUG DESIGN & DISCOVERY, 2015, 12 (08) : 687 - 693
[3] ULTRASOUND-ASSISTED SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NOVEL BENZOXAZINONYLHYDRAZONE DERIVATIVES
Chettibi, Naouel
Bentoumi, Houria
Liacha, Messaoud
REVUE ROUMAINE DE CHIMIE, 2020, 65 (10) : 885 - 891
[4] Ultrasound-assisted synthesis and anticancer evaluation of new pyrazole derivatives as cell cycle inhibitors
Nitulescu, George Mihai
Matei, Lilia
Aldea, Ioana Madalina
Draghici, Constantin
Olaru, Octavian Tudorel
Bleotu, Coralia
ARABIAN JOURNAL OF CHEMISTRY, 2019, 12 (06) : 816 - 824
[5] Synthesis and Antimicrobial Activity of Some Novel Hydrazide, Pyrazole, Triazine, Isoxazole, and Pyrimidine Derivatives
Refat, Hala M.
Fadda, A. A.
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2016, 53 (04) : 1129 - 1137
[6] Microwave assisted synthesis and antimicrobial activity of some novel pyrimidine derivatives
Vaghasia, S. J.
Shah, V. H.
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2007, 72 (02) : 109 - 117
[7] Ultrasound-assisted Synthesis and Characterization of 5-Carbonitrile-Functionalized tetrahydropyrimidine Derivatives with Evaluation of Their Antimicrobial Activity
Suthar, Madhuri J.
Kumbhani, Jasmin H.
Bhatt, Keyur D.
Bishnoi, Prakashbhai V.
Chatrabhuji, Parimal
ORIENTAL JOURNAL OF CHEMISTRY, 2024, 40 (01) : 281 - 287
[8] Synthesis, Antimicrobial and Antioxidant Activity of Pyrazole Based Sulfonamide Derivatives
Jagdish R. Badgujar
Dhananjay H. More
Jyotsna S. Meshram
Indian Journal of Microbiology, 2018, 58 : 93 - 99
[9] Synthesis, Antimicrobial and Antioxidant Activity of Pyrazole Based Sulfonamide Derivatives
Badgujar, Jagdish R.
More, Dhananjay H.
Meshram, Jyotsna S.
INDIAN JOURNAL OF MICROBIOLOGY, 2018, 58 (01) : 93 - 99
[10] Microwave-assisted synthesis of 1H-tetrazole-based flavonoid derivatives and their antimicrobial activity
Ashok, Dongamanti
Nagaraju, Nalaparaju
Sarasija, Madderla
Lakshmi, B. Vijaya
JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 2018, 83 (12) : 1305 - 1313

← 1 2 3 4 5 →