The novel G-quadruplex with hairpin loop formed immediately upstream of the human BCL-2 P1 promoter represses BCL-2 transcription

被引：0
|
作者：
Onel, Buket
Wu, Guanhui
Carver, Megan
Timonina, Daria
Larriva, Marti
Yang, Danzhou
机构：
来源：
CANCER RESEARCH | 2016年 / 76卷
关键词：
D O I：
10.1158/1538-7445.AM2016-2130
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2130
引用
收藏
页数：3
相关论文
共 50 条
  • [1] A New G-Quadruplex with Hairpin Loop Immediately Upstream of the Human BCL2 P1 Promoter Modulates Transcription
    Onel, Buket
    Carver, Megan
    Wu, Guanhui
    Timonina, Daria
    Kalarn, Salil
    Larriva, Marti
    Yang, Danzhou
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2016, 138 (08) : 2563 - 2570
  • [2] A novel G-quadruplex formed in the proximal P1 promoter of bcl-2 gene is a gene suppressor
    Onel, Buket
    Carver, Megan
    Yang, Danzhou
    CANCER RESEARCH, 2015, 75
  • [3] Novel G-quadruplex formed in the proximal P1 promoter of bcl-2 gene is a gene suppressor
    Onel, Buket
    Carver, Megan
    Yang, Danzhou
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [4] Novel loop interactions within a parallel-stranded G-quadruplex formed in the human BCL-2 proximal promoter
    Wu, Guanhui
    Lin, Clement
    Yang, Danzhou
    CANCER RESEARCH, 2017, 77
  • [5] Carbazole Derivatives Binding to Bcl-2 Promoter Sequence G-quadruplex
    Gluszynska, Agata
    Kosman, Joanna
    Chuah, Shang Shiuan
    Hoffmann, Marcin
    Haider, Shozeb
    PHARMACEUTICALS, 2024, 17 (07)
  • [6] Folding/unfolding kinetics of G-quadruplexes upstream of the P1 promoter of the human BCL-2 oncogene
    Cheng, Yuanlei
    Tang, Qingnan
    Li, Yutong
    Zhang, Yashuo
    Zhao, Chuyuan
    Yan, Jie
    You, Huijuan
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 294 (15) : 5890 - 5895
  • [7] Turning off Transcription of the bcl-2 Gene by Stabilizing the bcl-2 Promoter Quadruplex with Quindoline Derivatives
    Wang, Xiao-Dong
    Ou, Tian-Miao
    Lu, Yu-Jing
    Li, Zeng
    Xu, Zheng
    Xi, Chen
    Tan, Jia-Heng
    Huang, Shi-Liang
    An, Lin-Kun
    Li, Ding
    Gu, Lian-Quan
    Huang, Zhi-Shu
    JOURNAL OF MEDICINAL CHEMISTRY, 2010, 53 (11) : 4390 - 4398
  • [8] Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter
    Dexheimer, TS
    Sun, D
    Hurley, LH
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (16) : 5404 - 5415
  • [9] An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution
    Dai, Jixun
    Dexheimer, Thomas S.
    Chen, Ding
    Carver, Megan
    Ambrus, Attila
    Jones, Roger A.
    Yang, Danzhou
    Journal of the American Chemical Society, 2006, 128 (04): : 1096 - 1098
  • [10] General peroxidase activity of a parallel G-quadruplex-hemin DNAzyme formed by Pu39WT-a mixed G-quadruplex forming sequence in the Bcl-2 P1 promoter
    Liu, Bo
    Li, Da
    Shang, Hong
    CHEMISTRY CENTRAL JOURNAL, 2014, 8
12345