Lack of MicroRNA-101 Causes E-cadherin Functional Deregulation Through EZH2 Upregulation in Intestinal Gastric Cancer

被引:0
|
作者
Carvalho, J. [1 ]
van Grieken, N. [2 ]
Pereira, P. M. [3 ,4 ]
Diosdado, B. [2 ]
Santos, M. A. S. [3 ,4 ]
Meijer, G. [2 ]
Buffart, T. E. [2 ]
Seruca, R. [1 ]
Carvalho, B. [2 ]
Oliveira, C. [1 ]
机构
[1] IPATIMUP, Oporto, Portugal
[2] Vrije Univ Amsterdam, Med Ctr, Dept Pathol, Amsterdam, Netherlands
[3] Univ Aveiro, RNA Biol Lab, Dept Biol, P-3800 Aveiro, Portugal
[4] CESAM, Aveiro, Portugal
关键词
D O I
10.1016/S0959-8049(12)71248-0
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
591
引用
收藏
页码:S141 / S141
页数:1
相关论文
共 46 条
  • [1] Lack of microRNA-101 causes E-cadherin functional deregulation through EZH2 up-regulation in intestinal gastric cancer
    Carvalho, Joana
    van Grieken, Nicole C.
    Pereira, Patricia M.
    Sousa, Sonia
    Tijssen, Marianne
    Buffart, Tineke E.
    Diosdado, Begona
    Grabsch, Heike
    Santos, Manuel A. S.
    Meijer, Gerrit
    Seruca, Raquel
    Carvalho, Beatriz
    Oliveira, Carla
    JOURNAL OF PATHOLOGY, 2012, 228 (01): : 31 - 44
  • [2] Role of microRNA-101 in regulating histone methyltransferase EZH2 in cancer
    Cao, Qi
    Varambally, Sooryanarayana
    Mani, Ram-Shankar
    Shankar, Sunita
    Wang, Xiaosong
    Ateeq, Bushra
    Laxman, Bharathi
    Cao, Xuhong
    Ramnarayanan, Kalpana
    Jing, Xiaojun
    Brenner, J. Chad
    Yu, Jindan
    Kim, Jung
    Han, Bo
    Tan, Patrick
    Kumar-Sinha, Chandan
    Lonigro, Robert
    Palanisamy, Nallasivam
    Maher, Christopher
    Chinnaiyan, Arul
    CANCER RESEARCH, 2009, 69
  • [3] Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer
    Varambally, Sooryanarayana
    Cao, Qi
    Mani, Ram-Shankar
    Shankar, Sunita
    Wang, Xiaosong
    Ateeq, Bushra
    Laxman, Bharathi
    Cao, Xuhong
    Jing, Xiaojun
    Ramnarayanan, Kalpana
    Brenner, J. Chad
    Yu, Jindan
    Kim, Jung H.
    Han, Bo
    Tan, Patrick
    Kumar-Sinha, Chandan
    Lonigro, Robert J.
    Palanisamy, Nallasivam
    Maher, Christopher A.
    Chinnaiyan, Arul M.
    SCIENCE, 2008, 322 (5908) : 1695 - 1699
  • [4] Repression of E-cadherin by the polycomb group protein EZH2 in cancer
    Q Cao
    J Yu
    S M Dhanasekaran
    J H Kim
    R-S Mani
    S A Tomlins
    R Mehra
    B Laxman
    X Cao
    J Yu
    C G Kleer
    S Varambally
    A M Chinnaiyan
    Oncogene, 2008, 27 : 7274 - 7284
  • [5] Repression of E-cadherin by the polycomb group protein EZH2 in cancer
    Cao, Q.
    Yu, J.
    Dhanasekaran, S. M.
    Kim, J. H.
    Mani, R-S
    Tomlins, S. A.
    Mehra, R.
    Laxman, B.
    Cao, X.
    Yu, J.
    Kleer, C. G.
    Varambally, S.
    Chinnaiyan, A. M.
    ONCOGENE, 2008, 27 (58) : 7274 - 7284
  • [6] Repression of E-Cadherin by the Polycomb Group Protein EZH2 in Pancreatic Cancer
    Toll, A. D.
    Dasgupta, A.
    Potoczek, M.
    Kleer, C. G.
    Brody, J. R.
    Witkiewicz, A. K.
    LABORATORY INVESTIGATION, 2010, 90 : 372A - 372A
  • [7] Repression of E-Cadherin by the Polycomb Group Protein EZH2 in Pancreatic Cancer
    Toll, A. D.
    Dasgupta, A.
    Potoczek, M.
    Kleer, C. G.
    Brody, J. R.
    Witkiewicz, A. K.
    MODERN PATHOLOGY, 2010, 23 : 372A - 372A
  • [8] HOX transcript antisense intergenic RNA represses E-cadherin expression by binding to EZH2 in gastric cancer
    Wen-Ming Chen
    Wei-Dong Chen
    Xue-Mei Jiang
    Xue-Feng Jia
    Hong-Mei Wang
    Qiu-Jie Zhang
    Yong-Qian Shu
    Hai-Bo Zhao
    World Journal of Gastroenterology, 2017, (33) : 6100 - 6110
  • [9] HOX transcript antisense intergenic RNA represses E-cadherin expression by binding to EZH2 in gastric cancer
    Chen, Wen-Ming
    Chen, Wei-Dong
    Jiang, Xue-Mei
    Jia, Xue-Feng
    Wang, Hong-Mei
    Zhang, Qiu-Jie
    Shu, Yong-Qian
    Zhao, Hai-Bo
    WORLD JOURNAL OF GASTROENTEROLOGY, 2017, 23 (33) : 6100 - 6110
  • [10] Predictive value of the interaction of E-cadherin and EZH2 protein expression in prostate cancer
    Kuefer, R
    Shen, RL
    Schumacher, L
    Rhodes, DR
    Mattfeldt, T
    Chinnaiyan, AM
    Rubin, MA
    LABORATORY INVESTIGATION, 2003, 83 (01) : 157A - 158A