Classification and definition of major flares in SLE clinical trials

被引：237

作者：

Petri, M

Buyon, J

Kim, M

机构：

[1] Johns Hopkins Univ, Sch Med, Div Rheumatol, Baltimore, MD 21205 USA

[2] Hosp Joint Dis, New York, NY USA

[3] New York Med Ctr, Dept Environm Med, New York, NY USA

来源：

LUPUS | 1999年 / 8卷 / 08期

关键词：

systemic lupus erythematosus; flare; disease activity; SLEDAI;

D O I：

10.1191/096120399680411281

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Multiple reliable and valid disease activities indices exist and have been used successfully in longitudinal studies. However, the definition of flare, using these intruments, has not been universally decided or accepted. Because flare is one of the three major patterns of lupus activity, it will remain an important outcome measure in both longitudinal and clinical trial studies.

引用

页码：685 / 691

页数：7

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