Brefeldin A and Other Chemical Constituents from Endophytic Fungus Scedosporium apiospermum

被引:1
|
作者
Cordeiro, Jorgeffson da Silva [1 ]
Carvalho, Josiwander Miranda [1 ]
Feitosa, Andre de Oliveira [1 ]
Abreu Pinheiro, Eduardo Antonio [1 ]
Barbosa Marinho, Patricia Santana [1 ]
do Rosario Marinho, Andrey Moacir [1 ]
机构
[1] Fed Univ Para, Coll Chem, BR-66075110 Belem, Para, Brazil
关键词
Brefeldin A; Scedosporium; endophytic fungus;
D O I
10.21577/1984-6835.20190015
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This study reports the isolation of five compounds of Scedosporium apiospermum EJCP13 isolated as an endophytic of Bauhinia guianensis, a typical plant of the Amazon. The compounds brefeldin A (1), ergosterol (2), ergosterol peroxide (3), cerevisterol (4) and ducitol (5) were isolated by chromatographic procedures and identified by spectroscopic methods of 1D and 2D NMR and MS. The compound brefeldin A (1) showed a good antimicrobial activity and the compounds 1-5 are reported for the first time in Scedosporium genera.
引用
收藏
页码:210 / 217
页数:8
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