Myocardial Uncoupling Protein-2 Expression Depolarizes the Inner Membrane Potential of Mitochondria and Reduces Maximal Superoxide Levels

被引:0
|
作者
Ziemba, Elizabeth
Cabrera, Jesus A.
Colbert, Robbie
Sikora, Joseph
Ward, Herbert
Arriaga, Edgar
Duncker, Dirk J.
Sluiter, Wim
Kelly, Rosemary
McFalls, Edward O.
机构
[1] Univ Minnesota, VA Med Cntr, Minneapolis, MN USA
[2] Erasmus MC, Rotterdam, Netherlands
关键词
Metabolism; Mitochondria; Oxidative stress; Super oxide; Cardioprotection;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A9344
引用
收藏
页数:2
相关论文
共 10 条
  • [1] Uncoupling protein-2 expression and effects on mitochondrial membrane potential and oxidant stress in heart tissue
    Cabrera, Jesus A.
    Ziemba, Elizabeth A.
    Colbert, Robert
    Kelly, Rosemary F.
    Kuskowski, Michael
    Arriaga, Edgar A.
    Sluiter, Wim
    Duncker, Dirk J.
    Ward, Herbert B.
    Mcfalls, Edward O.
    TRANSLATIONAL RESEARCH, 2012, 159 (05) : 383 - 390
  • [2] Uncoupling protein-2 accumulates rapidly in the inner mitochondrial membrane during mitochondrial reactive oxygen stress in macrophages
    Giardina, Tindaro M.
    Steer, James H.
    Lo, Susan Z. Y.
    Joyce, David A.
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2008, 1777 (02): : 118 - 129
  • [3] Mitochondrial uncoupling protein 2 expression is increased and maximal superoxide production is decreased within chronically ischemic myocardium
    McFalls, EO
    Sluiter, W
    Schoonderwoerd, K
    Manintveld, OC
    Lamers, JM
    Bezstarosti, K
    van Beusekom, H
    Merkus, D
    Duncker, DJ
    CIRCULATION, 2005, 112 (17) : U115 - U115
  • [4] Effect of Shenfuyixin formula on the content of ATP and expression of uncoupling protein-2 in rats with heart failure following myocardial infarction
    Xie Shiyang
    Wang, Youping
    Wang, Xiaoxiao
    Li, Bin
    Chen, Peng
    Zhu, Cuiling
    Zhu, Mingjun
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2016, 68 (16) : C56 - C56
  • [5] Uncoupling protein-2 expression and activity in white adipocytes: modulation of mitochondrial membrane potential and cellular redox state in response to lipid load and reactive oxygen species
    Ogston, N. C.
    Sharpe, M. A.
    Flachs, P.
    Ricquier, D.
    Kopecky, J.
    Duchen, M. R.
    Mohamed-Ali, V.
    DIABETIC MEDICINE, 2007, 24 : 41 - 41
  • [6] Association of uncoupling protein-2 expression with increased reactive oxygen species in residual myocardium of the enlarged left ventricle after myocardial infarction
    Peng Guo
    Katsufumi Mizushige
    Takahisa Noma
    Kazushi Murakami
    Tsunetatsu Namba
    Makoto Ishizawa
    Teppei Tsuji
    Shoji Kimura
    Masakazu Kohno
    Heart and Vessels, 2005, 20 : 61 - 65
  • [7] Association of uncoupling protein-2 expression with increased reactive oxygen species in residual myocardium of the enlarged left ventricle after myocardial infarction
    Guo, P
    Mizushige, K
    Noma, T
    Murakami, K
    Namba, T
    Ishizawa, M
    Tsuji, T
    Kimura, S
    Kohno, M
    HEART AND VESSELS, 2005, 20 (02) : 61 - 65
  • [8] Expression of eosinophil target SNAREs as potential cognate receptors for vesicle-associated membrane protein-2 in exocytosis
    Logan, MR
    Lacy, P
    Bablitz, B
    Moqbel, R
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2002, 109 (02) : 299 - 306
  • [9] In vivo gene silencing of uncoupling protein-2 in kidney cortex of diabetic rats results in increased uncoupling, decreased oxidative stress and reduced membrane potential Implications for the adenine nucleotide transporter
    Friederich, Malou
    Nordquist, Lina
    Wilcox, Christopher S.
    Palm, Fredrik
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2010, 1797 : 86 - 87
  • [10] Increased expression levels of Syntaxin 1A and Synaptobrevin 2/Vesicle-Associated Membrane Protein-2 are associated with the progression of bladder cancer
    Raja, Sadaf Azad
    Abbas, Seher
    Shah, Syed Tahir Abbas
    Tariq, Aamira
    Bibi, Nazia
    Yousuf, Arzu
    Khawaja, Athar
    Nawaz, Muhammad
    Mehmood, Arshad
    Khan, Muhammad Jadoon
    Hussain, Alamdar
    GENETICS AND MOLECULAR BIOLOGY, 2019, 42 (01) : 40 - 47