Translating diagnostics and drug delivery technologies to low-resource settings

被引：13
|
作者：
Euliano, Erin M. [1 ]
Sklavounos, Alexandros A. [2 ,3 ]
Wheeler, Aaron R. [2 ,3 ,4 ]
McHugh, Kevin J. [1 ]
机构：
[1] Rice Univ, Dept Bioengn, Houston, TX 77005 USA
[2] Univ Toronto, Dept Chem, Toronto, ON M5S 3H6, Canada
[3] Univ Toronto, Donnelly Ctr Cellular & Biomol Res, Toronto, ON M5S 3E1, Canada
[4] Univ Toronto, Inst Biomed Engn, Toronto, ON M5S 3G9, Canada
来源：
SCIENCE TRANSLATIONAL MEDICINE | 2022年 / 14卷 / 666期
基金：
美国国家卫生研究院;
关键词：
MENINGOCOCCAL CONJUGATE VACCINE; AFRICAN MENINGITIS BELT; OF-CARE DIAGNOSTICS; AMPHOTERICIN-B; IMMUNOLOGICAL PARALYSIS; MICRONEEDLE PATCHES; CHOLESTERYL SULFATE; INFECTIOUS-DISEASES; INTRAVAGINAL RING; CONTRACEPTIVE USE;
D O I：
10.1126/scitranslmed.abm1732
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Diagnostics and drug delivery technologies engineered for low-resource settings aim to meet their technical design specifications using strategies that are compatible with limited equipment, infrastructure, and operator training. Despite many preclinical successes, very few of these devices have been translated to the clinic. Here, we identify factors that contribute to the clinical success of diagnostics and drug delivery systems for low-resource settings, including the need to engage key stakeholders at an early stage, and provide recommendations for the clinical translation of future medical technologies.
引用
收藏
页数：17
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