Generalized granuloma annulare associated with chronic hepatitis B virus infection

被引:18
|
作者
Ma, HJ [1 ]
Zhu, WY [1 ]
Yue, XZ [1 ]
机构
[1] Nanjing Med Univ, Dept Dermatol, Affiliated Hosp 1, Nanjing 210029, Jiangsu, Peoples R China
关键词
generalized granuloma annulare; hepatitis B virus infection;
D O I
10.1111/j.1468-3083.2005.01366.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We describe a 63-year-old Chinese woman with generalized granuloma annulare (GGA) associated with chronic hepatitis B virus (HBV) infection for 10 years. She developed non-annular papule lesions after a previous infection of hepatitis B virus. Since then, her clinical course was aggressive with involvement of the trunk, extremities and neck. Histologically, granulomatous inflammations were found in the upper to mid dermis. The HBV DNA in these lesions was demonstrated by polymerase chain reaction (PCR). GGA was totally regressed after treatment of interferon-alpha for 3 months. To the best of our knowledge, GGA associated with chronic HBV infection has never been reported in literature. The prognostic significance of the association of granulomatous inflammation and virus infection is reviewed.
引用
收藏
页码:186 / 189
页数:4
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