POST-HOC ANALYSIS FROM TWO PHASE I/II NY-ESO-1TCR T-CELL THERAPY CLINICAL TRIALS IN PATIENTS WITH ADVANCED SARCOMA (SS OR MRCLS) DEMONSTRATES RESPONSE ACROSS A RANGE OF NYESO-1 EXPRESSION

被引：1
|
作者：
Klohe, Erika [1 ]
Suchindran, Sunil [1 ]
Kapoor, Gurpreet [1 ]
D'Souza, Jimson [1 ]
Corigleano, Ellie [1 ]
Araujo, Dejka [2 ]
D'Angelo, Sandra [3 ]
机构：
[1] GlaxoSmithKline, Collegeville, PA USA
[2] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[3] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
来源：
JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2022年 / 10卷
关键词：
D O I：
10.1136/jitc-2022-SITC2022.0600
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
600
引用
收藏
页码：A628 / A629
页数：2
相关论文
共 5 条
  • [1] FINAL ANALYSIS OF THE PHASE 1 TRIAL OF NY-ESO-1-SPECIFIC T-CELL RECEPTOR (TCR) T-CELL THERAPY (LETETRESGENE AUTOLEUCEL; GSK3377794) IN PATIENTS WITH ADVANCED SYNOVIAL SARCOMA (SS)
    D'Angelo, Sandra
    Demetri, George
    Van Tine, Brian
    Druta, Mihaela
    Glod, John
    Chow, Warren
    Pandya, Naimish
    Hasan, Aisha
    Chiou, Victoria
    Tress, Jenna
    Edwards, Julie
    Young, Tim
    Woessner, Mary
    Gyuerdieva, Alexandra
    Zajic, Stefan
    Goodison, Sophia
    Araujo, Dejka
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 : A182 - A183
  • [2] ANALYSIS OF NY-ESO-1 EXPRESSION IN SPECIMENS FROM A PHASE I/II NY-ESO-1 T-CELL THERAPY CLINICAL TRIAL IN NON-SMALL CELL LUNG CANCER AND FROM EXPLORATORY STUDIES IN MULTIPLE TUMOR TYPES
    Barnes, Bryan
    Shan, Ming
    Blouch, Kristin
    Altan, Mehmet
    Kim, Jaegil
    Ramos-Hernandez, Natalia
    Corigliano, Ellie
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 : A482 - A482
  • [3] Phase I/II clinical trial of NY-ESO-1-specific TCR-engineered T-cell transfer combined with a novel T-cell stimulator CHP:NE1 for patients with refractory soft tissue sarcoma.
    Ishihara, Mikiya
    Hattori, Hiroyoshi
    Arai, Eisuke
    Nishida, Yoshihiro
    Takada, Kohichi
    Emori, Makoto
    Kawai, Akira
    Ueda, Takafumi
    Endo, Makoto
    Matsumoto, Yoshihiro
    Sasada, Tetsuro
    Sato, Eiichi
    Yamada, Tomomi
    Matsumine, Akihiko
    Nagata, Yasuhiro
    Harada, Naozumi
    Shiku, Hiroshi
    Kageyama, Shinichi
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [4] Results from phase I/II study of NY-ESO-1-specific TCR gene-transduced T cell therapy (TBI-1301, mipetresgene autoleucel) in patients with advanced synovial sarcoma
    Kawai, Akira
    Ishihara, Mikiya
    Nakamura, Tomoki
    Kitano, Shigehisa
    Iwata, Shintaro
    Takada, Kohichi
    Emori, Makoto
    Kato, Koji
    Endo, Makoto
    Matsumoto, Yoshihiro
    Kakunaga, Shigeki
    Sato, Eiichi
    Miyahara, Yoshihiro
    Morino, Kunihiko
    Tanaka, Shinya
    Takahashi, Shuichi
    Matsumine, Akihiko
    Kageyama, Shinichi
    Ueda, Takafumi
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [5] Safety and Efficacy of NY-ESO-1 Antigen-Specific T-Cell Receptor Gene-Transduced T Lymphocytes in Patients with Synovial Sarcoma: A Phase I/II Clinical Trial
    Kawai, Akira
    Ishihara, Mikiya
    Nakamura, Tomoki
    Kitano, Shigehisa
    Iwata, Shintaro
    Takada, Kohichi
    Emori, Makoto
    Kato, Koji
    Endo, Makoto
    Matsumoto, Yoshihiro
    Kakunaga, Shigeki
    Sato, Eiichi
    Miyahara, Yoshihiro
    Morino, Kunihiko
    Tanaka, Shinya
    Takahashi, Shuichi
    Matsuo, Fujio
    Matsumine, Akihiko
    Kageyama, Shinichi
    Ueda, Takafumi
    CLINICAL CANCER RESEARCH, 2023, 29 (24) : 5069 - 5078
1