Nucleophilic substitution reaction of 3-acetyl-1-methoxyindole and its application for the synthesis of novel 2-substituted methyl 2,3-dihydro-1-methyl-3-oxo-5H-pyrido-[4,3-b]indole-4-carboxylates

被引：12

作者：

Somei, M ^{[1
]}

Nakajou, M ^{[1
]}

Teramoto, T ^{[1
]}

Tanimoto, A ^{[1
]}

Yamada, F ^{[1
]}

机构：

[1] Kanazawa Univ, Fac Pharmaceut Sci, Kanazawa, Ishikawa 9200934, Japan

来源：

HETEROCYCLES | 1999年 / 51卷 / 08期

关键词：

D O I：

10.3987/COM-99-8608

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple synthetic route was established for 3-acetyl-1-methoxyindole, which was found to undergo nucleophilic substitution reactions selectively at the 2-position. Applying the reaction, novel 2-substituted methyl 2,3-dihydro-1-methyl-3-oxo-5H-pyrido[4,3-b]indole-4-carboxylates were prepared.

引用

页码：1949 / 1956

页数：8

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