Loss of bile salt export pump (Bsep/Abcb11) aggravates lipopolysaccharide induced hepatic inflammation in mice

被引:0
|
作者
Remetic, Jelena [1 ]
Mlitz, Veronika [1 ]
Kunczer, Victoria [1 ]
Schargl, Hubert [2 ]
Stojakovic, Tatjana [2 ]
Fuchs, Claudia [1 ]
Trauner, Michael [1 ]
机构
[1] Med Univ Vienna, Div Gastroenterol & Hepatol, Dept Internal Med 3, Vienna, Austria
[2] Med Univ Graz, Clin Inst Med & Chem Lab Diagnost, Graz, Austria
基金
奥地利科学基金会;
关键词
D O I
10.1016/S0618-8278(19)30305-6
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
THU-021
引用
收藏
页码:E169 / E169
页数:1
相关论文
共 50 条
  • [1] LOSS OF BILE SALT EXPORT PUMP (BSEP/Abcb11) AGGRAVATES LIPOPOLYSACCHARIDE-INDUCED HEPATIC INFLAMMATION IN MICE
    Remetic, Jelena
    Mlitz, Veronika
    Kunczer, Victoria
    Scharnagl, Hubert
    Stojakovic, Tatjana
    Fuchs, Claudia Daniela
    Trauner, Michael H.
    HEPATOLOGY, 2019, 70 : 812A - 813A
  • [2] Recent advances in the exploration of the bile salt export pump (BSEP/ABCB11) function
    Telbisz, Agnes
    Homolya, Laszlo
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2016, 20 (04) : 501 - 514
  • [3] The Canalicular Bile Salt Export Pump BSEP (ABCB11) as a Potential Therapeutic Target
    Stieger, Bruno
    Beuers, Ulrich
    CURRENT DRUG TARGETS, 2011, 12 (05) : 661 - 670
  • [4] Loss of bile salt export pump (BSEP/ABCB11) protects mice from development of carbon tetrachloride (CCl4) induced hepatic fibrosis
    Fuchs, Claudia
    Dixon, Emmanuel Dauda
    Konigshofer, Philipp
    Mlitz, Veronika
    Scharnagl, Hubert
    Stojakovic, Tatjana
    Reiberger, Thomas
    Trauner, Michael
    JOURNAL OF HEPATOLOGY, 2022, 77 : S469 - S469
  • [5] OVEREXPRESSION OF THE BILE SALT EXPORT PUMP (ABCB11) IN ABCB4-DEFICIENT MICE AGGRAVATES LIVER FIBROSIS
    Weber, S. N.
    Mahler, M.
    Plantz, V.
    Schmitz, A.
    Lammert, F.
    JOURNAL OF HEPATOLOGY, 2011, 54 : S360 - S360
  • [6] Absence of Bsep/Abcb11 attenuates MCD diet-induced hepatic steatosis but aggravates inflammation in mice
    Fuchs, Claudia D.
    Krivanec, Sebastian
    Steinacher, Daniel
    Mlitz, Veronika
    Wahlstroem, Annika
    Stahlman, Marcus
    Claudel, Thierry
    Scharnagl, Hubert
    Stojakovic, Tatjana
    Marschall, Hanns-Ulrich
    Trauner, Michael
    LIVER INTERNATIONAL, 2020, 40 (06) : 1366 - 1377
  • [7] Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin
    Hirano, M
    Maeda, K
    Hayashi, H
    Kusuhara, H
    Sugiyama, Y
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2005, 314 (02): : 876 - 882
  • [8] Regulatory mechanisms of the bile salt export pump (BSEP/ABCB11) and its role in related diseases
    Ren, Tengqi
    Pang, Liwei
    Dai, Wanlin
    Wu, Shuodong
    Kong, Jing
    CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY, 2021, 45 (06)
  • [9] Production and characterization of feline and canine bile salt export pump (BSEP; ABCB11) containing vesicles
    Van Beusekom, C. D.
    Schrickx, J. A.
    Fink-Gremmels, J.
    JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 2012, 35 : 159 - 159
  • [10] UBIQUITINATION IS ASSOCIATED WITH THE INTERNALIZATION OF BILE SALT EXPORT PUMP (BSEP/ABCB11) FROM THE PLASMA MEMBRANE
    Aida, Kensuke
    Hayashi, Hisamitsu
    Inamura, Kaori
    Mizuno, Tadahaya
    Sugiyama, Yuichi
    HEPATOLOGY, 2011, 54 : 725A - 726A