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- [1] Characterization and preclinical development of LY2603618: a selective and potent Chk1 inhibitorInvestigational New Drugs, 2014, 32 : 213 - 226Constance King论文数: 0 引用数: 0 h-index: 0机构: Lilly Research Laboratories,Henry Diaz论文数: 0 引用数: 0 h-index: 0机构: Lilly Research Laboratories,Darlene Barnard论文数: 0 引用数: 0 h-index: 0机构: Lilly Research Laboratories,David Barda论文数: 0 引用数: 0 h-index: 0机构: Lilly Research Laboratories,David Clawson论文数: 0 引用数: 0 h-index: 0机构: Lilly Research Laboratories,Wayne Blosser论文数: 0 引用数: 0 h-index: 0机构: Lilly Research Laboratories,Karen Cox论文数: 0 引用数: 0 h-index: 0机构: Lilly Research Laboratories,Sherry Guo论文数: 0 引用数: 0 h-index: 0机构: Lilly Research Laboratories,Mark Marshall论文数: 0 引用数: 0 h-index: 0机构: Lilly Research Laboratories,
- [2] Characterization and preclinical development of LY2603618: a selective and potent Chk1 inhibitorINVESTIGATIONAL NEW DRUGS, 2014, 32 (02) : 213 - 226King, Constance论文数: 0 引用数: 0 h-index: 0机构: Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USADiaz, Henry论文数: 0 引用数: 0 h-index: 0机构: Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USABarnard, Darlene论文数: 0 引用数: 0 h-index: 0机构: Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USABarda, David论文数: 0 引用数: 0 h-index: 0机构: Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USAClawson, David论文数: 0 引用数: 0 h-index: 0机构: Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USABlosser, Wayne论文数: 0 引用数: 0 h-index: 0机构: Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USACox, Karen论文数: 0 引用数: 0 h-index: 0机构: Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USAGuo, Sherry论文数: 0 引用数: 0 h-index: 0机构: Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USAMarshall, Mark论文数: 0 引用数: 0 h-index: 0机构: Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA Eli Lilly & Co, Lilly Res Labs, Indianapolis, IN 46285 USA
- [3] Targeting the replication checkpoint with a potent and selective CHK1 inhibitorCANCER RESEARCH, 2009, 69Parry, David论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Biopharma, Palo Alto, CA USAShanahan, Frances论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Biopharma, Palo Alto, CA USADavis, Nicole论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Biopharma, Palo Alto, CA USAWiswell, Derek论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Biopharma, Palo Alto, CA USASeghezzi, Wolfgang论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Biopharma, Palo Alto, CA USAPierce, Robert论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Biopharma, Palo Alto, CA USAHsieh, Yunsheng论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Biopharma, Palo Alto, CA USAParuch, Kamil论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Biopharma, Palo Alto, CA USAGuzi, Timothy论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Biopharma, Palo Alto, CA USA
- [4] Characterization and preclinical development of LY2606368, a second generation Chk1 inhibitorEJC SUPPLEMENTS, 2010, 8 (07): : 65 - 65Marshall, M.论文数: 0 引用数: 0 h-index: 0机构: Lilly Res Labs, Oncol Res, Indianapolis, IN USA Lilly Res Labs, Oncol Res, Indianapolis, IN USAKing, C.论文数: 0 引用数: 0 h-index: 0机构: Lilly Res Labs, Oncol Res, Indianapolis, IN USA Lilly Res Labs, Oncol Res, Indianapolis, IN USABarnard, D.论文数: 0 引用数: 0 h-index: 0机构: Lilly Res Labs, Oncol Res, Indianapolis, IN USA Lilly Res Labs, Oncol Res, Indianapolis, IN USADiaz, H.论文数: 0 引用数: 0 h-index: 0机构: Lilly Res Labs, Oncol Res, Indianapolis, IN USA Lilly Res Labs, Oncol Res, Indianapolis, IN USABarda, D.论文数: 0 引用数: 0 h-index: 0机构: Lilly Res Labs, Med Chem, Indianapolis, IN USA Lilly Res Labs, Oncol Res, Indianapolis, IN USABence, A.论文数: 0 引用数: 0 h-index: 0机构: Lilly Res Labs, Oncol Business Unit, Indianapolis, IN USA Lilly Res Labs, Oncol Res, Indianapolis, IN USAWestin, E.论文数: 0 引用数: 0 h-index: 0机构: Lilly Res Labs, Oncol Business Unit, Indianapolis, IN USA Lilly Res Labs, Oncol Res, Indianapolis, IN USA
- [5] New chk1 inhibitor development & the feasibility of use of chk1 inhibitor with antimetabolite for NSCLCCANCER RESEARCH, 2017, 77Chung, Injae论文数: 0 引用数: 0 h-index: 0
- [6] Preclinical characterization of ARRY-575: a potent, selective, and orally bio-available small molecule inhibitor of Chk1ANNALS OF ONCOLOGY, 2011, 22 : 23 - 23Humphries, M. J.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USAvon Carlowitz, I.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USALe Huerou, Y. L.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USARandolph, N.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USAGunawardana, I.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USAMohr, P. J.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USAWang, B.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USALyon, M. A.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USAChicarelli, M.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USASullivan, F.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USABlake, J. F.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USAWinski, S. L.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USAWallace, E.论文数: 0 引用数: 0 h-index: 0机构: Array BioPharma, Boulder, CO USA Array BioPharma, Boulder, CO USA
- [7] Characterization of a novel, oral Chk1 inhibitorCANCER RESEARCH, 2009, 69von Carlowitz, Ira论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USALe Huerou, Yvan论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USAHumphries, Michael论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USAGanster, Susan论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USARaddatz, Nicholas论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USARandolph, Nikole论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USASullivan, Francis论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USAMohr, Peter论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USAWang, Bin论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USAGunawardana, Indrani论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USAChicarelli, Mark论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USALyon, Michael论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USABlake, James论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USASchrag, Michael论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USAWinski, Shannon论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USAWallace, Eli论文数: 0 引用数: 0 h-index: 0机构: Array Biopharma, Boulder, CO USA Array Biopharma, Boulder, CO USA
- [8] Synthesis and development of potent Chk1 kinase inhibitorsABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238Huang, Shaei论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Med Chem, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAGarbaccio, Rob论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Med Chem, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USATasber, Edward S.论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Med Chem, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAFraley, Mark E.论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Med Chem, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USASteen, Justin T.论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Med Chem, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAYan, Youwei论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Biol Struct, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAMunshi, Sanjieev论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Biol Struct, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAIkuta, Mari论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Biol Struct, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAKuo, Lawrence论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Biol Struct, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAKreatsoulas, Constantine论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Biol Struct, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAReilly, Michael论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Drug Metab, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAMahan, Elizabeth论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Drug Metab, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAStirdivant, Steve论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USADrakas, Bob论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USARickert, Keith论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAWalsh, Eileen论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAHamilton, Kelly论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USABuser, Carolyn A.论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAHardwick, James论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAMao, Xianzhi论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USABeck, Steve论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAAbrams, Marc论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USATao, Weikang论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USALobell, Rob论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USASepp-Lorenzino, Laura论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Dept Canc Res, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USAHartman, George D.论文数: 0 引用数: 0 h-index: 0机构: Merck & Co Inc, Med Chem, West Point, PA 19486 USA Merck & Co Inc, Med Chem, West Point, PA 19486 USA
- [9] Characterization of the CHK1 Allosteric Inhibitor Binding SiteBIOCHEMISTRY, 2009, 48 (41) : 9823 - 9830Vanderpool, Darin论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USAJohnson, Ted O.论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Chem, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USAPing, Chen论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Struct & Computat Biol, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USABergqvist, Simon论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USAAlton, Gordon论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USAPhonephaly, Soneprasith论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USARui, Eugene论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Chem, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USALuo, Chun论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Struct & Computat Biol, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USADeng, Ya-Li论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Struct & Computat Biol, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USAGrant, Stephan论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USAQuenzer, Terri论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Struct & Computat Biol, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USAMargosiak, Steve论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USARegister, James论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USABrown, Ed论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USAErmolieff, Jacques论文数: 0 引用数: 0 h-index: 0机构: Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USA Pfizer, Dept Biochem & Primary Screening, San Diego, CA 92121 USA
- [10] Investigational CHK1 inhibitors in early phase clinical trials for the treatment of cancerEXPERT OPINION ON INVESTIGATIONAL DRUGS, 2019, 28 (12) : 1095 - 1100Dent, Paul论文数: 0 引用数: 0 h-index: 0机构: Virginia Commonwealth Univ, Dept Biochem & Mol Biol, Richmond, VA 23298 USA Virginia Commonwealth Univ, Dept Biochem & Mol Biol, Richmond, VA 23298 USA