Thioesterase Superfamily Member 2 (Them2) Channels Fatty Acids to Glycerol-3-Phosphate Acyltransferase-1 (GPAT1): Role in Hepatic Insulin Resistance

被引：0

作者：

Minami, Akihiro ^{[1
]}

Cooper, Daniel ^{[2
]}

Coleman, Rosalind ^{[2
]}

Cohen, David ^{[1
]}

机构：

[1] Harvard Univ, Brigham & Womens Hosp, Sch Med, Med, Boston, MA 02115 USA

[2] Univ N Carolina, Nutr, Chapel Hill, NC USA

来源：

FASEB JOURNAL | 2015年 / 29卷

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

LB173

引用

页数：1

共 32 条

[1] Thioesterase Superfamily Member 2 (Them2) Enables Glycerol-3-Phosphate Acyltransferase 1 (GPAT1) to Promote Glucose Intolerance in the Setting of Hepatic Steatosis
Tillander, Veronika
Minami, Akihiro
Coleman, Rosalind A.
Cohen, David E.
HEPATOLOGY, 2016, 64 : 127A - 127A
[2] Thioesterase superfamily member 2 promotes hepatic insulin resistance in the setting of glycerol-3-phosphate acyltransferase 1-induced steatosis
Tillander, Veronika
Miniami, Akihiro
Alves-Bezerra, Michele
Coleman, Rosalind A.
Cohen, David E.
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 294 (06) : 2009 - 2020
[3] Thioesterase Superfamily Member 2 (Them2) Promotes the Hepatic Oxidation of Plasma Free Fatty Acids
Kang, Hye Won
Han, Shuxin
Cohen, David E.
FASEB JOURNAL, 2012, 26
[4] Immune response to viral infection in mice lacking glycerol-3-phosphate acyltransferase 1 (GPAT1) is dysfunctional
不详
FASEB JOURNAL, 2008, 22
[5] Mitochondrial glycerol-3-phosphate acyltransferase-1 directs the metabolic fate of exogenous fatty acids in hepatocytes
Lewin, TM
Wang, SL
Nagle, CA
Van Horn, CG
Coleman, RA
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2005, 288 (05): : E835 - E844
[6] Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase-1 causes insulin resistance
Nagle, Cynthia A.
An, Jie
Newgard, Christopher B.
Coleman, Rosalind A.
FASEB JOURNAL, 2007, 21 (05): : A699 - A699
[7] Glycerol-3-phosphate Acyltransferase (GPAT)-1, but Not GPAT4, Incorporates Newly Synthesized Fatty Acids into Triacylglycerol and Diminishes Fatty Acid Oxidation
Wendel, Angela A.
Cooper, Daniel E.
Ilkayeva, Olga R.
Muoio, Deborah M.
Coleman, Rosalind A.
JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 288 (38) : 27299 - 27306
[8] Phosphatidylcholine Transfer Protein (PC-TP) and Thioesterase Superfamily Member 2 (Them2) Exacerbate Endoplasmic Reticulum (ER) Stress: Pathogenic Role in Insulin Resistance
Ersoy, Baran A.
Ozcan, Umut
Cohen, David E.
DIABETES, 2011, 60 : A59 - A59
[9] THIOESTERASE SUPERFAMILY MEMBER 2 (THEM2)/ACYL-COA THIOESTERASE 13 (ACOT13) PROMOTES FATTY ACID OXIDATION IN HEPATOCYTES: IMPLICATIONS FOR HEPATIC TRIGLYCERIDE HOMEOSTASIS
Kawano, Yuki
Li, Yingxia
Cohen, David E.
HEPATOLOGY, 2011, 54 : 1170A - 1171A
[10] PHOSPHATIDYLCHOLINE TRANSFER PROTEIN (PC-TP) AND THIOESTERASE SUPERFAMILY MEMBER 2 (THEM2) REGULATE INSULIN SIGNALING VIA INSULIN RECEPTOR SUBSTRATE 2 (IRS2): A NEW TARGET IN THE MANAGEMENT OF HEPATIC INSULIN RESISTANCE
Ersoy, Baran A.
Cohen, David E.
HEPATOLOGY, 2011, 54 : 394A - 394A

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