Derivative spectrophotometric determination of moclobemide in pharmaceutical formulations

被引：0
|
作者：
Patel, M. B. [1 ]
Patel, S. S. [1 ]
Patel, G. S. [1 ]
机构：
[1] Nootan Pharm Coll, Ahmadabad 380061, Gujarat, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2008年 / 20卷 / 04期
关键词：
moclobemide; first-derivative spectrophoto-metry;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A first derivative UV spectroscopic method was developed for determination of moclobemide in the tablet dosage form. The first derivative spectrum recorded between 200 and 300 nm and a zero-crossing technique for first derivative measurement at 225 nm was selected. The linear concentration ranges were 2-16 mu g/mL, r = 0.9994, n = 5). Between days CV % = 2.8. within day CV % = 2.1. analytical recovery close to 98.37-101.08 % shows the suitability of the method for determination in quality control.
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页码：3295 / 3297
页数：3
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