Detection of thrombin based on aptamer isothermal exponential signal amplification technique

被引：5
|
作者：
Shen, Xiaotong [1 ]
Zhang, Menghua [2 ]
Niu, Shuyan [1 ]
Shi, Chao [2 ]
机构：
[1] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Shandong Prov Key Lab Biochem Anal, Qingdao 266042, Peoples R China
[2] Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Minist Educ, Key Lab Sensor Anal Tumor Marker, Qingdao 266042, Peoples R China
来源：
ANALYST | 2015年 / 140卷 / 19期
基金：
中国国家自然科学基金;
关键词：
ROLLING-CIRCLE AMPLIFICATION; HIGHLY SENSITIVE DETECTION; STRAND DISPLACEMENT AMPLIFICATION; ULTRASENSITIVE DETECTION; DNA AMPLIFICATION; PROTEIN; MOLECULES; DIAGNOSTICS; MICROARRAYS; COCAINE;
D O I：
10.1039/c5an01313e
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In this report, a strategy based on an aptameric molecule switch to realize homogeneous and isothermal signal exponential amplification and protein detection has been described. This method was simple and sensitive, allowing detection of as low as 2.6 x 10(-12) M thrombin.
引用
收藏
页码：6489 / 6492
页数：4
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