Ganglionic eminence graft pre-eminence in epilepsy

被引：2
|
作者：
Parent, Jack M. [1 ,2 ]
Murphy, Geoffrey G. [2 ,3 ]
机构：
[1] Univ Michigan, Med Ctr, Dept Neurol, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Med Ctr, Grad Program Neurosci, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Med Ctr, Dept Mol & Integrat Physiol, Mol & Behav Neurosci Inst, Ann Arbor, MI 48109 USA
来源：
NATURE NEUROSCIENCE | 2013年 / 16卷 / 06期
关键词：
TEMPORAL-LOBE EPILEPSY; CORTICAL INTERNEURONS;
D O I：
10.1038/nn.3406
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Intrahippocampal transplantation of inhibitory interneuron progenitors derived from the medial ganglionic eminence markedly ameliorates the seizure activity and neurobehavioral deficits typically observed in the pilocarpine mouse model of mesial temporal lobe epilepsy, even if the cells are engrafted after the onset of spontaneous seizures.
引用
收藏
页码：656 / 658
页数：3
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