D3S-001, a highly potent, selective, and differentiated covalent inhibitor of KRAS G12C: Human dose prediction and first-in-human (FIH) trial design.

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作者
Lu, Jingtao [1 ]
Zhang, Jing [1 ]
Zheng, Zhiqiang [1 ]
Chen, Cheng [1 ]
Wang, Jia [1 ]
Chen, Janet [1 ]
Lu, Jiang [1 ]
Rui, Haopeng [1 ]
Wang, Allison [1 ]
Chen, Zhi Jian [1 ]
机构
[1] D3 Bio Wuxi Co Ltd, Shanghai, Peoples R China
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R73 [肿瘤学];
学科分类号
100214 ;
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15087
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