Inhibition of 6-phosphofructo-2-kinase suppresses breast tumor growth in vivo.

被引:0
|
作者
Clem, B. [1 ]
Telang, S. [1 ]
Clem, A. [1 ]
Goswami, U. [1 ]
Chesney, J. [1 ]
机构
[1] Univ Louisville, Louisville, KY 40292 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:223S / 223S
页数:1
相关论文
共 50 条
  • [1] Small molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth
    Clem, Brian F.
    Telang, Sucheta
    Clem, Amy
    Yalcin, Abdullah
    Meier, Jason
    Simmons, Alan
    Rasku, Mary Ann
    Arumugam, Sengodagounder
    Dean, William L.
    Eaton, John
    Lane, Andrew
    Trent, John O.
    Chesney, Jason
    MOLECULAR CANCER THERAPEUTICS, 2007, 6 (12) : 3363S - 3363S
  • [2] Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth
    Clem, Brian
    Telang, Sucheta
    Clem, Amy
    Yalcin, Abdullah
    Meier, Jason
    Simmons, Alan
    Rasku, Mary Ann
    Arumugam, Sengodagounder
    Dean, William L.
    Eaton, John
    Lane, Andrew
    Trent, John O.
    Chesney, Jason
    MOLECULAR CANCER THERAPEUTICS, 2008, 7 (01) : 110 - 120
  • [3] Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation
    Telang, Sucheta
    Clem, Brian F.
    Klarer, Alden C.
    Clem, Amy L.
    Trent, John O.
    Bucala, Richard
    Chesney, Jason
    JOURNAL OF TRANSLATIONAL MEDICINE, 2012, 10
  • [4] Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer
    Julie O’Neal
    Amy Clem
    Lindsey Reynolds
    Susan Dougherty
    Yoannis Imbert-Fernandez
    Sucheta Telang
    Jason Chesney
    Brian F. Clem
    Breast Cancer Research and Treatment, 2016, 160 : 29 - 40
  • [5] Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer
    O'Neal, Julie
    Clem, Amy
    Reynolds, Lindsey
    Dougherty, Susan
    Imbert-Fernandez, Yoannis
    Telang, Sucheta
    Chesney, Jason
    Clem, Brian F.
    BREAST CANCER RESEARCH AND TREATMENT, 2016, 160 (01) : 29 - 40
  • [6] INHIBITION OF 6-PHOSPHOFRUCTO-2-KINASE ACTIVITY BY MERCAPTOPURINES
    MOJENA, M
    BOSCA, L
    RIDER, MH
    ROUSSEAU, GG
    HUE, L
    BIOCHEMICAL PHARMACOLOGY, 1992, 43 (04) : 671 - 678
  • [7] Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation
    Sucheta Telang
    Brian F Clem
    Alden C Klarer
    Amy L Clem
    John O Trent
    Richard Bucala
    Jason Chesney
    Journal of Translational Medicine, 10
  • [8] Characterization of a novel small molecule antagonist of 6-phosphofructo-2-kinase that suppresses glucose metabolism and tumor growth
    Clem, Brian
    Tapolsky, Gilles H.
    O'Neal, Julie
    Chand, Pooran
    Clem, Amy
    Trent, John
    Telang, Sucheta
    Chesney, Jason
    CANCER RESEARCH, 2011, 71
  • [9] YEAST 6-PHOSPHOFRUCTO-2-KINASE
    YAMASHOJI, S
    HESS, B
    FEBS LETTERS, 1984, 172 (01): : 51 - 54
  • [10] Inhibition of tumor cell growth by a specific 6-phosphofructo-2-kinase inhibitor, N-bromoacetylethanolamine phosphate, and its analogues
    Hirata, T
    Watanabe, M
    Miura, S
    Ijichi, K
    Fukasawa, M
    Sakakibara, R
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2000, 64 (10) : 2047 - 2052