Exploiting small molecule and siRNA libraries to identify novel mechanisms for potential cancer therapeutic agents

被引:0
|
作者
Lazo, John Stephen [1 ]
McDonald, Peter R. [1 ]
Wipf, Peter [1 ]
机构
[1] Univ Pittsburgh, Pittsburgh, PA USA
来源
FASEB JOURNAL | 2008年 / 22卷
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Design and production of sultam libraries as potential small molecule therapeutic agents
    Hanson, Paul R.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
  • [2] Transcript Profiling and RNA Interference as Tools To Identify Small Molecule Mechanisms and Therapeutic Potential
    Palchaudhuri, Rahul
    Hergenrother, Paul J.
    ACS CHEMICAL BIOLOGY, 2011, 6 (01) : 21 - 33
  • [4] Therapeutic potential of a novel small molecule, PRLX 93936, in models of pancreatic cancer
    Robbins, Paul
    Pierce, Michael
    Venkat, Raj Gopal
    Clemens, Christopher
    Rebentisch, Matthew
    Lai, Shuping
    Senina, Anna
    Becklin, Robert
    VanWagenen, Brad
    O'Mel, Vlad
    Peltier, John
    Erkkila, Tracy
    Sahasrabudhe, Sudhir
    CANCER RESEARCH, 2009, 69
  • [5] Novel Small Molecule Aldehyde Sequestering Agents Demonstrate Broad Therapeutic Potential for Ocular Inflammation
    Macdonald, Susan
    Halilovic, Adna
    Brady, Todd
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2018, 59 (09)
  • [6] Small-molecule inhibitors of breast cancer-related targets: Potential therapeutic agents for breast cancer
    Liu, Tingting
    Song, Shubin
    Wang, Xu
    Hao, Jifu
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 210
  • [7] Therapeutic potential of siRNA and DNAzymes in cancer
    Karnati, Hanuma Kumar
    Yalagala, Ravi Shekar
    Undi, Rambabu
    Pasupuleti, Satya Ratan
    Gutti, Ravi Kumar
    TUMOR BIOLOGY, 2014, 35 (10) : 9505 - 9521
  • [8] Assessing novel small molecule drugs as potential new therapeutic options to treat colorectal cancer
    Moriarity, A. R.
    Murphy, A.
    Cathcart, M.
    Kennedy, B. N.
    Murphy, P.
    McCormick, P. H.
    O'Sullivan, J. N.
    Mehigan, B. J.
    IRISH JOURNAL OF MEDICAL SCIENCE, 2013, 182 : S37 - S37
  • [9] Small-molecule PROTACs: novel agents for cancer therapy
    Wan, Yichao
    Yan, Chunxing
    Gao, Han
    Liu, Tingting
    FUTURE MEDICINAL CHEMISTRY, 2020, 12 (10) : 915 - 938
  • [10] Mechanisms of Intrinsic Radioresistance in Breast Cancer Identify Potential Therapeutic Vulnerabilities
    McBean, B.
    Michmerhuizen, A. R.
    Wilder-Romans, K.
    Chandler, B.
    Lerner, L.
    Ward, C.
    Liu, M.
    Boyle, A. P.
    Speers, C.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2023, 117 (02): : E250 - E250