Is critical care ready for an economic surrogate endpoint?

被引：10

作者：

Wilcox, M. Elizabeth ^{[1
,2
]}

Rubenfeld, Gordon D. ^{[2
,3
,4
]}

机构：

[1] Univ Hlth Network, Toronto Western Hosp, Dept Med, Toronto, ON M5T 2S8, Canada

[2] Univ Toronto, Interdept Div Crit Care, Toronto, ON M4N 3M5, Canada

[3] Sunnybrook Hlth Sci Ctr, Dept Crit Care Med, Toronto, ON M4N 3M5, Canada

[4] Sunnybrook Hlth Sci Ctr, Sunnybrook Res Inst, Toronto, ON M4N 3M5, Canada

来源：

CRITICAL CARE | 2015年 / 19卷

关键词：

LENGTH-OF-STAY; INTENSIVE-CARE; COST-EFFECTIVENESS; IMPACT;

D O I：

10.1186/s13054-015-0947-0

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Intensive care is expensive, and thus a body of research has focused on strategies to reduce its costs. However, efforts to reduce the total cost of intensive care have met with limited success, partly because of the challenges of calculating how much a day in the ICU actually costs. We discuss these challenges and introduce the concept of total cost savings as an outcome of critical care trials, assuming statistically negative effects on mortality and quality of life.

引用

页数：3

共 50 条

[1] Is critical care ready for an economic surrogate endpoint?
M Elizabeth Wilcox
Gordon D Rubenfeld
Critical Care, 19
[2] Are you ready to move into critical care?
Cottrell, Damon
Kendall, Stephanie M.
AMERICAN JOURNAL OF NURSING, 2010, : 20 - 21
[3] Change in albuminuria as a surrogate endpoint
Waijer, Simke W.
Gansevoort, Ron T.
Heerspink, Hiddo J. L.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2019, 28 (06): : 519 - 526
[4] Establishing and Using Threshold of Surrogate Endpoint in Relation to Clinical Endpoint
Cheng, Yu-Chieh
Tsou, Hsiao-Hui
Hung, H. M. James
Fan, Byron
Fan, Brandon
STATISTICS IN BIOPHARMACEUTICAL RESEARCH, 2024,
[5] Transformation: are nurse leaders in critical care ready?
Botma, Yvonne
Botha, Hanlie
Nel, Mariette
JOURNAL OF NURSING MANAGEMENT, 2012, 20 (07) : 921 - 927
[6] Clinical potential of microdystrophin as a surrogate endpoint
Boehler, Jessica F.
Brown, Kristy J.
Beatka, Margaret
Gonzalez, J. Patrick
Dreghici, Roxana Donisa
Soustek-Kramer, Meghan
McGonigle, Sharon
Ganot, Annie
Palmer, Timothy
Lowie, Caitlin
Chamberlain, Jeffrey S.
Lawlor, Michael W.
Morris, Carl A.
NEUROMUSCULAR DISORDERS, 2023, 33 (01) : 40 - 49
[7] pCR Proves Valid Surrogate Endpoint
不详
CANCER DISCOVERY, 2014, 4 (02) : 137 - 138
[8] Pathological complete response as a surrogate endpoint
Sorscher, Steven
BREAST, 2017, 33 : 202 - 202
[9] Microalbuminuria as Surrogate Endpoint in Therapeutic Trials
Redon, Josep
Martinez, Fernando
CURRENT HYPERTENSION REPORTS, 2012, 14 (04) : 345 - 349
[10] Microalbuminuria as Surrogate Endpoint in Therapeutic Trials
Josep Redon
Fernando Martinez
Current Hypertension Reports, 2012, 14 : 345 - 349

← 1 2 3 4 5 →