Implantation du dispositif XEN 45? dans la chirurgie du glaucome : ?tude bicentrique bispective s?int?ressant au glaucome cortisonique par rapport au glaucome primitif ? angle ouvert

被引：1

作者：

Cornee, C. ^{[1
]}

Orignac, I ^{[1
]}

Wargny, M. ^{[1
]}

Clement, M. ^{[1
]}

Varnier, C. ^{[1
]}

Le Meur, G. ^{[1
]}

Lebranchu, P. ^{[1
]}

Weber, M. ^{[1
]}

机构：

[1] CHU Nantes, Serv Ophtalmol, 1 Pl Alexis Ricordeau, F-44000 Nantes, France

来源：

JOURNAL FRANCAIS D OPHTALMOLOGIE | 2022年 / 45卷 / 08期

关键词：

XEN 45? gel stent; Intraocular pressure; Steroid-induced glaucoma; Primary open angle glaucoma; Minimally Invasive Glaucoma Surgery; Filtering surgery; Needling; Uveitis;

D O I：

10.1016/j.jfo.2022.04.007

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Introduction. - XEN 45 (R) gel stent is an ab interno aqueous humor drainage device indicated for moderate glaucoma refractory to medical management. Its efficacy has been demonstrated in primary open-angle glaucoma (POAG). However, there are few studies on secondary glaucoma, including steroid-induced glaucoma (CG), defined as optic neuropathy induced by using local or systemic corticosteroids without increased flare.Methods. - We conducted a dual-center comparative cohort study between April 2019 and January 2021. 66 operated eyes were included, divided into two groups: POAG (56 eyes) and GC (10 eyes). The primary endpoint was the relative reduction in intraocular pressure (IOP) at three months postoperatively in the GC group. Three outcomes were defined: total success, partial success and failure.Results. - The total success rate was 100% in the GC group and 42.6% in the POAG group. Preoperative IOP was 36.1 +/- 9.1 mmHg and 19.0 +/- 7.3 mmHg respectively. IOP reduction was 69.1 +/- 11.7% in the GC group and 21.8 +/- 30.3% in the POAG group. Patients were younger in the GC group (49.3 +/- 21.2 versus 71.1 +/- 8.4 years), and preoperative conjunctival preparation was longer in this group (12 versus 5 weeks). The needling rate was 17.9% in the POAG group and 10% in the GC group.Conclusion. - The XEN 45 (R) gel stent is effective in the treatment of steroid-induced glaucoma. Further studies will be required to identify predictive factors for success and to establish criteria for good candidacy.(c) 2022 Elsevier Masson SAS. All rights reserved.

引用

页码：872 / 882

页数：11